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A naturalistic study of treatment outcomes with aripiprazole in young people with first episode psychosis

Dodd, Seetal, Callaly, Tom, Thampi, Annette, McConnell, Stephen, Hantz, Paul, Goodman, Derek, Kohlmann, Kristy, Vieira da Silva Magalhaes, Pedro and Berk, Michael 2010, A naturalistic study of treatment outcomes with aripiprazole in young people with first episode psychosis, Clinical psychopharmacology and neuroscience, vol. 8, no. 2, pp. 105-110.

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Title A naturalistic study of treatment outcomes with aripiprazole in young people with first episode psychosis
Author(s) Dodd, Seetal
Callaly, Tom
Thampi, Annette
McConnell, Stephen
Hantz, Paul
Goodman, Derek
Kohlmann, Kristy
Vieira da Silva Magalhaes, Pedro
Berk, Michael
Journal name Clinical psychopharmacology and neuroscience
Volume number 8
Issue number 2
Start page 105
End page 110
Total pages 6
Publisher Korean College of Neuropsychopharmacology
Place of publication Seoul, Korea
Publication date 2010-08
ISSN 1738-1088
2093-4327
Keyword(s) Aripiprazole
First-episode psychosis
Treatment
Outcomes
Schizophrenia
Bipolar disorder
Summary Objective: Adequate treatment of a first psychotic episode in young people is a difficult challenge but may be of critical importance for changing the course of psychotic illness. Pharmacotherapy is the standard treatment of psychosis, however there is a paucity of data specific to first-episode psychosis.
Methods: In this study 12 young people who presented with a psychotic episode at a specialised early intervention service were commenced on treatment with aripiprazole. They were assessed at baseline and weeks 4, 6, 24 and 48 using a broad battery of outcome measures. Case notes were also examined.
Results: Data was available for 6 participants at week 48, and of those, one remained on treatment with Aripiprazole at endpoint. Case histories were typified by presentations that included illicit substance use and treatments characterised by several changes in medications. No single treatment choice predominated. Most participants tolerated treatment and showed symptomatic improvement with individualised therapy.
Conclusion: Most participants showed improvement during the treatment period. Aripiprazole was one of many medications used in this study and may have been useful for the treatment of some individuals with first episode psychosis.
Language eng
Field of Research 111714 Mental Health
Socio Economic Objective 920410 Mental Health
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2010, Korean College of Neuropsychopharmacology
Persistent URL http://hdl.handle.net/10536/DRO/DU:30031104

Document type: Journal Article
Collections: School of Medicine
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.