Invited editorial presents an accurate summary of the results of two randomised placebo-controlled trials of vertebroplasty

Buchbinder, Rachelle, Osborne, Richard H and Kallmes, David 2010, Invited editorial presents an accurate summary of the results of two randomised placebo-controlled trials of vertebroplasty, Medical journal of Australia, vol. 192, no. 6, pp. 338-341.

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Title Invited editorial presents an accurate summary of the results of two randomised placebo-controlled trials of vertebroplasty
Author(s) Buchbinder, Rachelle
Osborne, Richard H
Kallmes, David
Journal name Medical journal of Australia
Volume number 192
Issue number 6
Start page 338
End page 341
Publisher Australasian Medical Publishing Company Pty Ltd
Place of publication Strawberry Hills, N.S.W.
Publication date 2010-03-15
ISSN 0025-729X
1326-5377
Summary Our recent editorial in the Journal presents an accurate summary of our two randomised trials of vertebroplasty, which found no benefit of vertebroplasty over placebo.

Participants in both trials are representative of patients seen in clinical practice and who would qualify for government-subsidised funding of vertebroplasty in Australia.

Clinical experience and previous published literature are likely to have overestimated the treatment benefit of vertebroplasty for many reasons.

This is why randomised placebo-controlled trials are required to determine the efficacy of treatment interventions, particularly when the condition being treated is self-limiting and the primary end point is improvement of symptoms.

Based on the best evidence currently available, the routine use of vertebroplasty outside of the research setting for painful osteoporotic vertebral fractures appears unjustified.
Language eng
Field of Research 111717 Primary Health Care
Socio Economic Objective 920205 Health Education and Promotion
HERDC Research category C2 Other contribution to refereed journal
Copyright notice ©2010, Australasian Medical Publishing Company
Persistent URL http://hdl.handle.net/10536/DRO/DU:30031209

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Created: Wed, 17 Nov 2010, 10:22:37 EST by Jane Moschetti

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