Receptor mediated tumor targeting : an emerging approach for cancer therapy Mohanty, Chandana, Das, Manasi, Kanwar, Jagat R. and Sahoo, Sanjeeb K. 2011, Receptor mediated tumor targeting : an emerging approach for cancer therapy, Current drug delivery, vol. 8, no. 1, pp. 45-58. Attached Files Name Description MIMEType Size Downloads Title Receptor mediated tumor targeting : an emerging approach for cancer therapy Author(s) Mohanty, Chandana Das, Manasi Kanwar, Jagat R. Sahoo, Sanjeeb K. Journal name Current drug delivery Volume number 8 Issue number 1 Start page 45 End page 58 Total pages 14 Publisher Bentham Science Publishers Place of publication Bussum, Netherlands Publication date 2011-01-01 ISSN 1567-2018 1875-5704 Keyword(s) receptor ligand nanocarrier tumor targeting Summary Receptor-mediated tumor targeting has received major attention in the field of cancer drug delivery in the past few years. Receptors, as molecular target has opened new opportunities for cellular or intracellular targeting of drug loaded delivery systems conjugated with targeting moieties i.e. ligand. This receptor mediated targeting of cancer drug through nano carrier sys¬tems to cancerous tissue offer protection and improves the pharmacokinetics of various drugs and help to overcome the systemic toxicity and adverse effects that result from the non-selective nature of most current cancer therapeutic agents. The article reviews the scope of receptor mediated targeting of anticancer drug loaded in various nanocarriers and also summarize recent perspective and challenges in the field of nanocarrier-aided drug delivery and drug targeting for cancer therapy. Language eng Field of Research 060199 Biochemistry and Cell Biology not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1 Refereed article in a scholarly journal Persistent URL http://hdl.handle.net/10536/DRO/DU:30031508 Document type: Journal Article Collection: Centre for Biotechnology and Interdisciplinary Sciences (BioDeakin)   Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Thu, 09 Dec 2010, 09:26:17 EST Tue, 14 Dec 2010, 10:44:41 EST Tue, 14 Dec 2010, 10:56:09 EST Tue, 14 Dec 2010, 13:59:47 EST Tue, 14 Dec 2010, 14:04:18 EST Thu, 13 Jan 2011, 09:23:33 EST Thu, 13 Jan 2011, 09:28:07 EST Tue, 18 Jan 2011, 11:05:24 EST Tue, 18 Jan 2011, 11:07:09 EST Wed, 15 Jun 2011, 15:37:26 EST Wed, 15 Jun 2011, 16:20:56 EST Thu, 01 Mar 2012, 09:58:18 EST Thu, 01 Mar 2012, 11:41:47 EST Thu, 01 Mar 2012, 11:43:00 EST Filtered Full Citation counts:   Cited 35 times in TR Web of Science Cited 35 times in Scopus Search Google Scholar Access Statistics: 564 Abstract Views, 3 File Downloads  -  Detailed Statistics Created: Thu, 09 Dec 2010, 09:26:14 EST by Kislay Roy

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