Is this D vitamin to worry about? Vitamin D insufficiency in an inpatient sample

Berk, Michael, Jacka, Felice N., Williams, Lana J., Ng, Felicity, Dodd, Seetal and Pasco, Julie A. 2008, Is this D vitamin to worry about? Vitamin D insufficiency in an inpatient sample, Australian and New Zealand journal of psychiatry, vol. 42, no. 10, pp. 874-878.

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Title Is this D vitamin to worry about? Vitamin D insufficiency in an inpatient sample
Author(s) Berk, Michael
Jacka, Felice N.
Williams, Lana J.
Ng, Felicity
Dodd, Seetal
Pasco, Julie A.
Journal name Australian and New Zealand journal of psychiatry
Volume number 42
Issue number 10
Start page 874
End page 878
Publisher Informa Healthcare
Place of publication Abingdon, England
Publication date 2008-10
ISSN 0004-8674
1440-1614
Keyword(s) depression
screening
vitamin D
Summary Objective: The aim of the present study was to investigate the relationship between reduced serum vitamin D levels and psychiatric illness.

Method: This study was an audit of serum 25-hydroxyvitamin D (25-OHD) levels measured routinely in a sample of 53 inpatients in a private psychiatric clinic. These levels were compared with those of controls without psychiatric illness.

Results: The median levels of serum 25-OHD were 43.0 nmol L−1 (range 20–102 nmol L−1) in the patient population, 46.0 nmol L−1 (range 20–102 nmol L−1) in female patients (n =33) and 41.5 nmol L−1 (range 22–97 nmol L−1) in male patients (n =20). The proportion of vitamin D insufficiency (serum 25-OHD ≤50 nmol L−1) in this patient population was 58%. Furthermore, 11% had moderate deficiency (serum 25-OHD ≤25 nmol L−1). There was a 29% difference between mean levels in the patient population and control sample (geometric mean age- and season-adjusted levels: 46.4 nmol L−1 (95% confidence interval (CI) =38.6–54.9 nmol L−1) vs 65.3 nmol L−1 (95%CI =63.2–67.4 nmol L−1), p <0.001).

Conclusion: Low levels of serum 25-OHD were found in this patient population. These data add to the literature suggesting an association between vitamin D insufficiency and psychiatric illness, and suggest that routine monitoring of vitamin D levels may be of benefit given the high yield of clinically relevant findings.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Related work DU:30042980
Copyright notice ©2008, Informa Healthcare
Persistent URL http://hdl.handle.net/10536/DRO/DU:30033151

Document type: Journal Article
Collection: School of Medicine
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