Assessing health risk of reclaimed water using human cell culture.

Ackland, M. L., Michalczyk, A. A., Freestone, D. and Stagnitti, F. 2010, Assessing health risk of reclaimed water using human cell culture., Water, vol. 37, no. 8, pp. 39-43.

Attached Files
Name Description MIMEType Size Downloads

Title Assessing health risk of reclaimed water using human cell culture.
Author(s) Ackland, M. L.ORCID iD for Ackland, M. L.
Michalczyk, A. A.ORCID iD for Michalczyk, A. A.
Freestone, D.
Stagnitti, F.
Journal name Water
Volume number 37
Issue number 8
Start page 39
End page 43
Total pages 5
Publisher Australian Water Association
Place of publication St Leonards, N.S.W.
Publication date 2010-12
ISSN 0310-0367
Summary For risk analysis of reclaimed water, current animal and toxicity testing may not detect subtle effects such as interactions that could contribute to complex diseases such as cancers that develop over a long period of time. There is a need for assays that can be validated against known human physiological processes. We have previously validated sensitive human cell culture assays for their responsiveness to agents that induce carcinogenesis in vivo. In this initial study we analysed the effects of three batches of reclaimed water on human colonic cells. At concentrations of up to 10-fold, they had no significant effect on the cellular markers, indicating an overall lack of biological activity. The assay has potential but needs to be refined to maximise its sensitivity.
Language eng
Field of Research 060199 Biochemistry and Cell Biology not elsewhere classified
050206 Environmental Monitoring
Socio Economic Objective 970110 Expanding Knowledge in Technology
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2010, Australian Water Association
Persistent URL

Connect to link resolver
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 0 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 775 Abstract Views, 4 File Downloads  -  Detailed Statistics
Created: Mon, 14 Mar 2011, 12:30:47 EST by Teresa Treffry

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact