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Forearm blood flow in individuals with CHF and age-matched healthy volunteers : a study and historical review

Patterson, Jeremy, Selig, Steve, Toia, Deidre, Bamroongsuk, Voramont and Hare, David 2007, Forearm blood flow in individuals with CHF and age-matched healthy volunteers : a study and historical review, Journal of exercise physiology online, vol. 10, no. 5, pp. 1-15.

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Title Forearm blood flow in individuals with CHF and age-matched healthy volunteers : a study and historical review
Author(s) Patterson, Jeremy
Selig, Steve
Toia, Deidre
Bamroongsuk, Voramont
Hare, David
Journal name Journal of exercise physiology online
Volume number 10
Issue number 5
Start page 1
End page 15
Publisher American Society of Exercise Physiologists
Place of publication Duluth, Minn.
Publication date 2007-10
ISSN 1097-9751
Keyword(s) chronic heart failure
venous occlusion plethysmography
basal blood flow
ACE inhibitors
isometric exercise
Summary This study examined forearm blood flow (FBF) in individuals with chronic heart failure (CHF) at rest, moderate exercise, and following limb occlusion. FBF was measured by venous occlusion plethysmography in CHF patients (n = 43) and healthy age-matched volunteers (n = 8) at rest and during exercise consisting of intermittent isometric hand squeezing at 15, 30, and 45% of maximum voluntary contraction (MVC). Peak vasodilatory capacity was also determined following the release of an occluding arm cuff. FBF was lower in CHF patients during exercise and during peak reactive hyperemia (PRH) compared to healthy volunteers, but there was no significant difference between groups at rest. Peak vasodilatory capacity was significantly higher in healthy volunteers than the CHF group ((30.6 ± 8.6 ml±100 mL-1±min-1 and 18.3 ± 6.9 ml±100 mL-1±min-1, respectively). Local blood flow stimulation in response to exercise or limb occlusion is reduced in individuals with CHF, however, there was no difference in resting flows between the two groups, suggesting vasodilatory medication may restore resting blood flow to healthy values.
Notes Reproduced with the kind permission of the copyright owner.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, American Society of Exercise Physiologists
Persistent URL http://hdl.handle.net/10536/DRO/DU:30033432

Document type: Journal Article
Collections: School of Exercise and Nutrition Sciences
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.