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Evolution of lactation : ancient origin and extreme adaptations of the lactation system

Lefevre, Christophe, Sharp, Julie A. and Nicholas, Kevin R. 2010, Evolution of lactation : ancient origin and extreme adaptations of the lactation system, Annual review of genomics and human genetics, vol. 11, no. 1, pp. 219-238.

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Title Evolution of lactation : ancient origin and extreme adaptations of the lactation system
Author(s) Lefevre, Christophe
Sharp, Julie A.
Nicholas, Kevin R.
Journal name Annual review of genomics and human genetics
Volume number 11
Issue number 1
Start page 219
End page 238
Publisher Annual Reviews
Place of publication Palo Alto, Calif.
Publication date 2010
ISSN 1527-8204
1545-293X
Keyword(s) mammals
monotreme
marsupial
eutherian
milk
transcriptomics
caseins
LALBA
involution
Summary Lactation, an important characteristic of mammalian reproduction, has evolved by exploiting a diversity of strategies across mammals. Comparative genomics and transcriptomics experiments have now allowed a more in-depth analysis of the molecular evolution of lactation. Milk cell and mammary gland genomic studies have started to reveal conserved milk proteins and other components of the lactation system of monotreme, marsupial, and eutherian lineages. These analyses confirm the ancient origin of the lactation system and provide useful insight into the function of specific milk proteins in the control of lactation. These studies also illuminate the role of milk in the regulation of growth and development of the young beyond simple nutritive aspects.
Language eng
Field of Research 060408 Genomics
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2010, Annual Reviews
Persistent URL http://hdl.handle.net/10536/DRO/DU:30033814

Document type: Journal Article
Collection: Centre for Biotechnology and Interdisciplinary Sciences (BioDeakin)
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Created: Mon, 11 Apr 2011, 16:59:57 EST by Sandra Dunoon