Deakin home > Deakin University Library > Deakin Research Online > In vitro osteoblast-like cell proliferation on nano-hydroxyapatite coatings with different morphologies on a titanium-niobium shape memory alloy

In vitro osteoblast-like cell proliferation on nano-hydroxyapatite coatings with different morphologies on a titanium-niobium shape memory alloy

Xiong, Jianyu, Li, Yuncang, Hodgson, Peter D. and Wen, Cui'e 2010, In vitro osteoblast-like cell proliferation on nano-hydroxyapatite coatings with different morphologies on a titanium-niobium shape memory alloy, Journal of biomedical materials research part A, vol. 95A, no. 3, pp. 766-773.

Attached Files (Some files may be inaccessible until you login with your Deakin Research Online credentials)
Name Description MIMEType Size Downloads

Title In vitro osteoblast-like cell proliferation on nano-hydroxyapatite coatings with different morphologies on a titanium-niobium shape memory alloy
Formatted title In vitro osteoblast-like cell proliferation on nano-hydroxyapatite coatings with different morphologies on a titanium-niobium shape memory alloy
Author(s) Xiong, Jianyu
Li, Yuncang
Hodgson, Peter D.
Wen, Cui'e
Journal name Journal of biomedical materials research part A
Volume number 95A
Issue number 3
Start page 766
End page 773
Publisher John Wiley & Sons, Inc
Place of publication Malden, Mass.
Publication date 2010-12-01
ISSN 1549-3296
1552-4965
Keyword(s) nano-hydroxyapatite coating
hydrothermal process
titanium-niobium alloy
osteoblast-like cells
in vitro proliferation
Summary The morphology of nanomaterials significantly affects their physical, chemical, and biological properties. In the present study, nano-hydroxyapatite coatings with different morphologies were produced on the surface of a titanium-niobium shape memory alloy via a hydrothermal process. The effect of the nano-hydroxyapatite coatings on the in vitro proliferation of SaOS-2 osteoblast-like cells was investigated. Factors including crystallinity, surface micro-roughness, and surface energy of the nano-hydroxyapatite coatings were discussed. Results show that in vitro proliferation of the osteoblast-like cells was significantly enhanced on the nano-hydroxyapatite-coated titanium-niobium alloy compared to the titanium-niobium alloy without coating. The cell numbers on the nano-hydroxyapatite-coated titanium-niobium alloy changed consistently with the surface energy of the hydroxyapatite coatings. This study suggests that surface energy as a characteristic parameter influencing the in vitro proliferation of osteoblast-like cells was predominant over the crystallinity and surface micro-roughness of the nano-hydroxyapatite coatings.
Language eng
Field of Research 090301 Biomaterials
Socio Economic Objective 861201 Coated Metal and Metal-Coated Products
HERDC Research category C1 Refereed article in a scholarly journal
HERDC collection year 2010
Copyright notice ©2010, Wiley Periodicals, Inc.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30034389

Document type: Journal Article
Collection: Centre for Material and Fibre Innovation
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in Deakin Research Online is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 5 times in TR Web of Science
Scopus Citation Count Cited 3 times in Scopus
Access Statistics: 179 Abstract Views, 1 File Downloads  -  Detailed Statistics
Created: Tue, 19 Apr 2011, 12:57:27 EST by Sandra Dunoon