Antidepressants and breast-feeding : a review of the literature

Dodd, Seetal, Buist, Anne and Norman, Trevor R. 2000, Antidepressants and breast-feeding : a review of the literature, Paediatric drugs, vol. 2, no. 3, pp. 183-192.

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Title Antidepressants and breast-feeding : a review of the literature
Author(s) Dodd, Seetal
Buist, Anne
Norman, Trevor R.
Journal name Paediatric drugs
Volume number 2
Issue number 3
Start page 183
End page 192
Publisher Adis International
Place of publication Auckland, N.Z.
Publication date 2000-05
ISSN 1174-5878
1179-2019
Summary For every antidepressant so far investigated in the breast milk of mothers prescribed these medications, findings indicate that some amount of drug will be excreted into the breast milk. Nursing infants will be exposed to some, usually a very low, amount of drug and drugmetabolites. Levels of drug exposure to infants for the many antidepressants available are examined, discussing milk to plasma drug concentration ratios and the infant dose as a percentage of thematernal dose. Drug concentrations in infant plasma and adverse effects of drug exposures to infants are reviewed. Factors influencing the decision on whether to breast or bottle feed an infant nursed by a mother taking antidepressants are discussed, concluding that the decision needs to be made on an individual basis. The lactating mother, in consultation with her doctor, should be in a position to make an informed decision on whether or not to breast feed. Under certain circumstances the decision to bottle feed may be wise, but more commonly the advantages of breast-feeding will outweigh the very low risk of an adverse event from drug exposure to the infant.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2000, Adis International
Persistent URL http://hdl.handle.net/10536/DRO/DU:30035598

Document type: Journal Article
Collection: School of Medicine
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