A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use

Jespersen, Sean, Berk, Michael, Van Wyk, Caren, Dean, Olivia, Dodd, Seetal, Szabo, Christopher P. and Maud, Catherine 2004, A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use, International clinical psychopharmacology, vol. 19, no. 3, pp. 161-164.

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Title A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use
Author(s) Jespersen, Sean
Berk, Michael
Van Wyk, Caren
Dean, Olivia
Dodd, Seetal
Szabo, Christopher P.
Maud, Catherine
Journal name International clinical psychopharmacology
Volume number 19
Issue number 3
Start page 161
End page 164
Publisher Lippincott Williams & Wilkins
Place of publication Philadelphia, Pa.
Publication date 2004-05
ISSN 0268-1315
Summary A pilot study was conducted to evaluate the usefulness of granisetron for the treatment of antidepressant induced sexual dysfunction in women. Twelve women with antidepressant induced sexual dysfunction (AISD) were assigned granisetron (n=5) or placebo (n=7) in a 14-day randomized, double-blind, placebo-controlled study. One participant in the granisetron group did not complete the study. Participants were assessed at baseline, day 7 and day 14 using the Feiger Sexual Function and Satisfaction Questionnaire and the Arizona Sexual Experience Scale. No statistical differences were measured at baseline or at endpoint between the granisetron or placebo group. This study did not produce evidence supporting the usefulness of granisetron in AISD.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2004, Lippincott Williams & Wilkins
Persistent URL http://hdl.handle.net/10536/DRO/DU:30035636

Document type: Journal Article
Collection: School of Medicine
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