Vitamin D, obesity, and obesity-related chronic disease among ethnic minorities : a systematic review

Renzaho, Andre M. N., Halliday, Jennifer A. and Nowson, Caryl 2011, Vitamin D, obesity, and obesity-related chronic disease among ethnic minorities : a systematic review, Nutrition, vol. 27, no. 9, pp. 868-879.

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Title Vitamin D, obesity, and obesity-related chronic disease among ethnic minorities : a systematic review
Alternative title Review : Vitamin D, obesity, and obesity-related chronic disease among ethnic minorities : a systematic review
Author(s) Renzaho, Andre M. N.
Halliday, Jennifer A.
Nowson, Caryl
Journal name Nutrition
Volume number 27
Issue number 9
Start page 868
End page 879
Publisher Elsevier Inc.
Place of publication New York, N.Y.
Publication date 2011-09
ISSN 0899-9007
Keyword(s) vitamin D
obesity
diabetes
cardiovascular disease
ethnic minority
Summary Objective : To assess the association between 25-hydroxyvitamin D (25[OH]D) status and obesity, cardiovascular diseases (CVDs), the metabolic syndrome, and type 2 diabetes mellitus (T2DM) in ethnic minorities.

Methods : Databases searched were CINHAL with full text, Global Health, MEDLINE with full text, and PsycINFO from 1980 through 2010 (February). Studies were included if they 1) targeted immigrants from low- to high-income countries or ethnic minorities, 2) focused primarily on 25(OH)D and its relation to obesity, T2DM, and/or CVDs, and 3) were published in peer-reviewed journals. The influences of key confounders such as age, gender, and ethnicity on any observed relations were also assessed. Due to the heterogeneity of study characteristics, only a narrative synthesis was undertaken.

Results :
Ethnic minorities had significantly higher rates of vitamin D insufficiency (25[OH]D <50 nmol/L; children 43.6–48.7% versus 10%; adults 30.3–53% versus 13.7–26%) than their white counterparts. None of the studies reported a prevalence of obesity stratified by ethnicity. There was evidence supporting links between vitamin D deficiency and obesity-related chronic diseases, with 14 of 14 studies reporting a statistically significant result with a measurement of obesity, four of five for T2DM, four of five for CVDs, and one of one for the metabolic syndrome. However, the strength of the association varied across ethnic groups depending on the index used to measure adiposity, T2DM, and CVDs. Because most of the included studies were cross-sectional and there were variations in outcome measurements, it was not possible to determine the relative contributions of obesity or vitamin D insufficiency to CVD risk and risk of T2DM or which is the initial driver It is possible both have a role to play.

Conclusion :
Further research specific to migrant populations using randomized controlled trials are required to establish whether causal links between 25(OH)D and obesity-related chronic disease exist, and whether vitamin D supplementation could be valuable in the prevention or treatment of obesity-related diseases.
Language eng
Field of Research 111799 Public Health and Health Services not elsewhere classified
Socio Economic Objective 920205 Health Education and Promotion
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
HERDC collection year 2011
Copyright notice ©2011, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30035880

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