DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS

Pfeffer, Frederick, Henderson, Luke, Li, Jian and Nation, Roger 2010, DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS, Other international (5) Patent WO 2010099573 (A1).


Title DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS
Creator(s) Pfeffer, Frederick
Henderson, Luke
Li, Jian
Nation, Roger
Date 2010-09-10
Patent no. WO 2010099573 (A1)
Patent owner UNIV DEAKIN, Frederick Pfeffer, Luke Henderson, Jian Li, Roger Nation
Registry Office Other international (5)
Patent family name DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS
Summary The invention provides a compound including : A core having a first face and a second face; A binding portion attached to the first face of the core, wherein the binding portion is capable of binding to an anionic group present in a cell membrane of a microorganism; and A hydrophobic portion attached to the second face of the core, wherein the hydrophobic portion is capable of interacting with the cell membrane of the microorganism; and The core comprises a dioxolane norbornane / norbornene of formula (II): Or a salt or ion thereof, wherein R' is a moiety forming part of a hydrophobic portion; R2 is a first binding portion; and R3 is a seconding binding portion. The invention also provides compositions including at least one such compound. The invention also provides methods and uses for treatment or prophylaxis of infection of a mammal by a microorganism, and methods and uses for treating or preventing contamination of a substrate by a microorganism, using the compounds and compositions.
Language eng
Field of Research 060501 Bacteriology
060599 Microbiology not elsewhere classified
HERDC Research category I Patents
ERA Research output type I Patents
Copyright notice ©2010, Deakin University, Frederick Pfeffer, Luke Henderson, Jian Li, Roger Nation
Persistent URL http://hdl.handle.net/10536/DRO/DU:30036020

Document type: Patent
Collection: School of Life and Environmental Sciences
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Access Statistics: 89 Abstract Views  -  Detailed Statistics
Created: Tue, 26 Jul 2011, 16:31:07 EST by Lesa Maclean

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.