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DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS

Pfeffer, Frederick, Henderson, Luke, Li, Jian and Nation, Roger 2010, DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS, Other international (5) Patent WO 2010099573 (A1).

Document type: Patent
Collection: School of Life and Environmental Sciences

Title DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS
Creator(s) Pfeffer, Frederick
Henderson, Luke
Li, Jian
Nation, Roger
Date 2010-09-10
Patent no. WO 2010099573 (A1)
Patent owner UNIV DEAKIN, Frederick Pfeffer, Luke Henderson, Jian Li, Roger Nation
Registry Office Other international (5)
Patent family name DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS
Summary The invention provides a compound including : A core having a first face and a second face; A binding portion attached to the first face of the core, wherein the binding portion is capable of binding to an anionic group present in a cell membrane of a microorganism; and A hydrophobic portion attached to the second face of the core, wherein the hydrophobic portion is capable of interacting with the cell membrane of the microorganism; and The core comprises a dioxolane norbornane / norbornene of formula (II): Or a salt or ion thereof, wherein R' is a moiety forming part of a hydrophobic portion; R2 is a first binding portion; and R3 is a seconding binding portion. The invention also provides compositions including at least one such compound. The invention also provides methods and uses for treatment or prophylaxis of infection of a mammal by a microorganism, and methods and uses for treating or preventing contamination of a substrate by a microorganism, using the compounds and compositions.
Language eng
Field of Research 060501 Bacteriology
060599 Microbiology not elsewhere classified
HERDC Research category I Patents
ERA Research output type I Patents
Copyright notice ©2010, Deakin University, Frederick Pfeffer, Luke Henderson, Jian Li, Roger Nation
Persistent URL http://hdl.handle.net/10536/DRO/DU:30036020
 
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Created: Tue, 26 Jul 2011, 16:31:07 EST by Lesa Maclean