The impact of hypoglycaemia on quality of life and related patient-reported outcomes in Type 2 diabetes : a narrative review

Barendse, S., Singh , H., Frier , B. M. and Speight, J. 2012, The impact of hypoglycaemia on quality of life and related patient-reported outcomes in Type 2 diabetes : a narrative review, Diabetic medicine, vol. 29, no. 3, pp. 293-302.

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Title The impact of hypoglycaemia on quality of life and related patient-reported outcomes in Type 2 diabetes : a narrative review
Author(s) Barendse, S.
Singh , H.
Frier , B. M.
Speight, J.
Journal name Diabetic medicine
Volume number 29
Issue number 3
Start page 293
End page 302
Total pages 10
Publisher Wiley-Blackwell Publishing
Place of publication Chichester, England
Publication date 2012
ISSN 0742-3071
1464-5491
Keyword(s) health status
type 2 diabetes
quality of life
patient reported outcomes
hypoglycaemia
Summary As a common side effect of insulin treatment for diabetes, hypoglycaemia is a constant threat and can have far-reaching and potentially devastating consequences, including immediate physical injury as well as more pervasive cognitive, behavioural and emotional effects. Moreover, as a significant limiting factor in achieving optimal glycaemic control, exposure to hypoglycaemia can influence diabetes self-management.

Although hypoglycaemia is known to occur in Type 2 diabetes, its morbidity and impact on the individual are not well recognized. The aim of the current review is to examine published evidence to achieve a synthesis of the scope and significance of the potential detriment caused by hypoglycaemia to individuals with Type 2 diabetes. The implications of these observations for treatment and research have also been considered.

A narrative review was performed of empirical papers published in English since 1966, reporting the effect of hypoglycaemia on quality of life and related outcomes (including generic and diabetes specificquality of life, emotional well-being and health utilities) in Type 2 diabetes.

Research demonstrates the potential impact of hypoglycaemia on the lives of people with Type 2 diabetes, from an association with depressive symptoms and heightened anxiety, to impairment of the ability to drive, work and function in ways that are important for quality of life. Few studies consider hypoglycaemia as an explanatory variable in combination with quality of life or related primary endpoints. As a consequence, there is a pressing need for high-quality research into the overall impact of hypoglycaemia on the lives of people with Type 2 diabetes.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2011, Wiley-Blackwell Publishing
Persistent URL http://hdl.handle.net/10536/DRO/DU:30036477

Document type: Journal Article
Collection: School of Psychology
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