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A preliminary analysis of the cost-effectiveness of the National Bowel Cancer Screening Program – demonstrating the potential value of comprehensive real world data

Tran, Ben, Keating, Catherine L., Ananda, Sumitra S., Kosmider, Suzanne, Jones, Ian, Croxford, Matthew, Field, Kathryn M., Carter, Rob C. and Gibbs, Peter 2012, A preliminary analysis of the cost-effectiveness of the National Bowel Cancer Screening Program – demonstrating the potential value of comprehensive real world data, Internal medicine journal, vol. 42, no. 7, pp. 794-800.

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Title A preliminary analysis of the cost-effectiveness of the National Bowel Cancer Screening Program – demonstrating the potential value of comprehensive real world data
Author(s) Tran, Ben
Keating, Catherine L.
Ananda, Sumitra S.
Kosmider, Suzanne
Jones, Ian
Croxford, Matthew
Field, Kathryn M.
Carter, Rob C.
Gibbs, Peter
Journal name Internal medicine journal
Volume number 42
Issue number 7
Start page 794
End page 800
Total pages 7
Publisher Wiley-Blackwell Publishing Asia
Place of publication Richmond, Vic.
Publication date 2012-07
ISSN 1444-0903
1445-5994
Keyword(s) colorectal cancer
FOBT screening
cost-effectiveness
Summary Background The complexity and cost of treating cancer patients is escalating rapidly and increasingly difficult decisions are being made regarding which interventions provide value for money. BioGrid Australia supports collection and analysis of comprehensive treatment and outcome data across multiple sites. Here we use preliminary data regarding the National Bowel Cancer Screening Program (NBCSP) and stage-specific treatment costs for colorectal cancer (CRC) to demonstrate the potential value of real world data for cost-effectiveness analyses (CEA).

Methods Data regarding the impact of NBCSP on stage at diagnosis was combined with stage-specific CRC treatment costs and existing literature. An incremental CEA was undertaken from a government healthcare perspective, comparing NBCSP to no-screening. The 2008 invited population (n=681,915) was modelled in both scenarios. Effectiveness was expressed as CRC-related life years saved (LYS). Costs and benefits were discounted at 3% per annum.

Results
Over the lifetime and relative to no-screening, NBCSP was predicted to save 1,265 life-years, prevent 225 CRC cases and cost an additional $48.3 million, equivalent to a cost-effectiveness ratio of $38,217 per LYS. A scenario analysis assuming full participation improved this to $23,395.

Conclusions
This preliminary CEA based largely on contemporary real world data suggests population-based FOBT screening for CRC is attractive. Planned ongoing data collection will enable repeated analyses over time, using the same methodology in the same patient populations, permitting an accurate analysis of the impact of new therapies and changing practice. Similar CEA using real world data related to other disease types and interventions appears desirable.
Notes Reproduced with the kind permission of the copyright owner.
Language eng
Field of Research 140208 Health Economics
Socio Economic Objective 920204 Evaluation of Health Outcomes
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2011, Wiley-Blackwell Publishing Asia
Persistent URL http://hdl.handle.net/10536/DRO/DU:30036931

Document type: Journal Article
Collections: Population Health
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