3D particle-based cell modelling for haptic microrobotic cell injection
Asgari, Marzieh, Ghanbari, Ali and Nahavandi, Saeid 2011, 3D particle-based cell modelling for haptic microrobotic cell injection, in ICMT 2011 : Proceedings of the 15th International Conference on Mechatronics Technology : Precision Mechatronics for Advanced Manufacturing, Service, and Medical Sectors, [ICMT], [Melbourne, Vic.], pp. 1-6.
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Introducing haptic interface to conduct microrobotic intracellular injection has many beneficial implications. In particular, the haptic device provides force feedback to the bio-operator's hand. This paper introduces a 3D particle-based model to simulate the deformation of the cell membrane and corresponding cellular forces during microrobotic cell injection. The model is based on the kinematic and dynamic of spring – damper multi particle joints considering visco-elastic fluidic properties. It simulates the indentation force feedback as well as cell visual deformation during the microinjection. The model is verified using experimental data of zebrafish embryo microinjection. The results demonstrate that the developed cell model is capable of estimating zebrafish embryo deformation and force feedback accurately.
Field of Research
080199 Artificial Intelligence and Image Processing not elsewhere classified
Socio Economic Objective
970108 Expanding Knowledge in the Information and Computing Sciences
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