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Lack of relationship between sedentary behaviour and vascular function in children

Hopkins, Nicola, Stratton, G., Ridgers, N. D., Graves, L. E. F., Cable, N. T. and Green, D. J. 2012, Lack of relationship between sedentary behaviour and vascular function in children, European journal of applied physiology, vol. 112, no. 2, pp. 617-622, doi: 10.1007/s00421-011-2011-3.

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Title Lack of relationship between sedentary behaviour and vascular function in children
Author(s) Hopkins, Nicola
Stratton, G.
Ridgers, N. D.ORCID iD for Ridgers, N. D. orcid.org/0000-0001-5713-3515
Graves, L. E. F.
Cable, N. T.
Green, D. J.
Journal name European journal of applied physiology
Volume number 112
Issue number 2
Start page 617
End page 622
Total pages 6
Publisher Springer
Place of publication Heidelberg, Germany
Publication date 2012
ISSN 1439-6319
1439-6327
Keyword(s) endothelial function
vasodilation
physical inactivity
accelerometry
Summary Some evidence suggests that sedentary behaviour is independently associated with cardiovascular (CV) risk. Endothelial dysfunction is the earliest detectable manifestation of CVD and a strong independent predictor of CV events. No previous study has examined the relationship between sedentary behaviour and endothelial function. We assessed the basal association between conduit artery endothelial function and sedentary behaviour in children, along with the correlation between changes in sedentary behaviour and endothelial function. We studied 116 children (70$: 10.7 ± 0.3; 46#: 10.7 ± 0.3 years) on two occasions; in the summer (June) and late autumn (November). We assessed endothelial function via flowmediated dilation (FMD) using high-resolution Doppler ultrasound. Sedentary behaviour (SB) was assessed using objective uni-axial accelerometry. At baseline, there were no significant differences between girls and boys for any measured variables with the exception of total physical activity time. FMD was not associated with sedentary behaviour in either group or in the cohort as a whole. Although FMD decreased (10.0 ± 4.3–7.9 ± 3.9%, P\0.001) and SB increased (499.1 ± 103.5–559 ± 81.6 min/day, P\0.001) between the seasons, no relationship existed between changes in these variables. Our data suggest that sedentary behaviour and changes in sedentary behaviour are not associated with endothelial function in children.
Language eng
DOI 10.1007/s00421-011-2011-3
Field of Research 111706 Epidemiology
Socio Economic Objective 920401 Behaviour and Health
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2011, Springer-Verlag
Persistent URL http://hdl.handle.net/10536/DRO/DU:30042698

Document type: Journal Article
Collection: Centre for Physical Activity and Nutrition Research
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Created: Tue, 28 Feb 2012, 09:47:48 EST by Jane Moschetti

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