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Hormone therapy and risk of non-vertebral fracture : Geelong Osteoporosis Study

Pasco, Julie A., Kotowicz, Mark A., Henry, Margaret J., Sanders, Kerrie M., Seeman, Ego and Nicholson, Geoffrey C. 2004, Hormone therapy and risk of non-vertebral fracture : Geelong Osteoporosis Study, Osteoporosis International, vol. 15, no. 6, pp. 434-438.

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Title Hormone therapy and risk of non-vertebral fracture : Geelong Osteoporosis Study
Author(s) Pasco, Julie A.
Kotowicz, Mark A.
Henry, Margaret J.
Sanders, Kerrie M.
Seeman, Ego
Nicholson, Geoffrey C.
Journal name Osteoporosis International
Volume number 15
Issue number 6
Start page 434
End page 438
Total pages 5
Publisher Springer U. K.
Place of publication Surrey, England
Publication date 2004
ISSN 0937-941X
Keyword(s) bone mineral density
fracture
hormone therapy
population-based study
postmenopausal women
Summary In this population-based study, we evaluated the association between exposure to hormone therapy (HT), bone mineral density (BMD) and the prevalence of non-vertebral fractures. The study was set in a region located in southeastern Australia where complete fracture ascertainment was determined from radiological reports. Current HT use for at least 6 months was ascertained in women with non-vertebral fractures [median age 70.9 years; inter-quartile range (IQR) 66.5–75.9 years] and randomly selected controls (median age 70.8 years; IQR 65.2–75.0 years). Current HT use was documented in 20 of 262 cases and 49 of 364 controls. The odds ratio (OR) for non-vertebral fracture associated with HT use was 0.53 (95% CI 0.31–0.92). HT use was associated with 2.6–7.5% higher BMD at axial and appendicular sites. HT use is associated with a halving of risk for non-vertebral fractures and higher BMD.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2004, International Osteoporosis Foundation and National Osteoporosis Foundation
Persistent URL http://hdl.handle.net/10536/DRO/DU:30042817

Document type: Journal Article
Collection: School of Medicine
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