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Biodegradable Mg-Zr-Ca alloys for bone implant materials

Li, Yuncang, Wong, C. S., Wen, C. and Hodgson, P. D. 2012, Biodegradable Mg-Zr-Ca alloys for bone implant materials, Materials technology, vol. 27, no. 1, pp. 49-51.

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Title Biodegradable Mg-Zr-Ca alloys for bone implant materials
Author(s) Li, Yuncang
Wong, C. S.
Wen, C.
Hodgson, P. D.
Journal name Materials technology
Volume number 27
Issue number 1
Start page 49
End page 51
Total pages 3
Publisher Maney Publishing
Place of publication Leeds, U. K.
Publication date 2012-02
ISSN 1066-7857
1753-5557
Keyword(s) corrosion and mechanical properties
cytotoxicity
biodegradable Mg-Zr-Ca alloy
Summary Mg–Zr–Ca alloys were developed for new biodegradable bone implant materials. The microstructure and mechanical property of the Mg–xZr–yCa [x=0·5, 1·0% and y=1·0, 2·0% (wt-% hereafter)] alloys were characterised by optical microscopy, compressive and hardness tests. The in vitro cytotoxicity of the alloys was assessed using osteoblast-like SaOS2 cells. The corrosion behaviour of these alloys was evaluated by soaking the alloys in simulated body fluid (SBF) and modified minimum essential medium (MMEM). Results indicated that the mechanical properties of the Mg–Zr–Ca are in the range of the mechanical properties of natural bone. The corrosion rate and biocompatibility decreases with the increase in the Ca content in the Mg–Zr–Ca alloys. The solutions of SBF and MMEM with the immersion of the Mg–Zr–Ca alloys show strong alkalisation. The Zr addition to the Mg–Zr–Ca alloys leads to an increase in the corrosion resistance, compressive strength and the ductility of the alloys, and a decrease in the elastic modulus of the Mg–Zr–Ca alloys.
Language eng
Field of Research 091309 Tribology
091207 Metals and Alloy Materials
090399 Biomedical Engineering not elsewhere classified
Socio Economic Objective 861206 Structural Metal Products
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2012, W. S. Maney & Son Ltd.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30044245

Document type: Journal Article
Collection: Institute for Technology Research and Innovation
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Created: Thu, 05 Apr 2012, 16:00:33 EST

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