Dielectrophoresis of micro/nano particles using curved microelectrodes
Khoshmanesh, Khashayar, Tovar-Lopez, Francisco J., Baratchi, Sara, Zhang, Chen, Kayani, Aminuddin A., Chrimes, Adam F., Nahavandi, Saeid, Wlodkowic, Donald, Mitchell, Arnan and Kalantar-zadeh, Kourosh 2011, Dielectrophoresis of micro/nano particles using curved microelectrodes, in SPIE 2011 : Proceedings of SPIE - The International Society for Optical Engineering, SPIE, Bellingham, Wash., pp. 1-9.
Dielectrophoresis, the induced motion of polarisable particles in non-homogenous electric field, has been proven as a versatile mechanism to transport, immobilise, sort and characterise micro/nano scale particle in microfluidic platforms. The performance of dielectrophoretic (DEP) systems depend on two parameters: the configuration of microelectrodes designed to produce the DEP force and the operating strategies devised to employ this force in such processes. This work summarises the unique features of curved microelectrodes for the DEP manipulation of target particles in microfluidic systems. The curved microelectrodes demonstrate exceptional capabilities including (i) creating strong electric fields over a large portion of their structure, (ii) minimising electro-thermal vortices and undesired disturbances at their tips, (iii) covering the entire width of the microchannel influencing all passing particles, and (iv) providing a large trapping area at their entrance region, as evidenced by extensive numerical and experimental analyses. These microelectrodes have been successfully applied for a variety of engineering and biomedical applications including (i) sorting and trapping model polystyrene particles based on their dimensions, (ii) patterning carbon nanotubes to trap low-conductive particles, (iii) sorting live and dead cells based on their dielectric properties, (iv) real-time analysis of drug-induced cell death, and (v) interfacing tumour cells with environmental scanning electron microscopy to study their morphological properties. The DEP systems based on curved microelectrodes have a great potential to be integrated with the future lab-on-a-chip systems.
Notes
Reproduced with the kind permission of the copyright owner.
ISBN
9780819488459
ISSN
0277-786X
Language
eng
Field of Research
091306 Microelectromechanical Systems (MEMS)
Socio Economic Objective
970106 Expanding Knowledge in the Biological Sciences
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.
Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO.
If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.
Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.