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Dielectrophoresis of micro/nano particles using curved microelectrodes

Khoshmanesh, Khashayar, Tovar-Lopez, Francisco J., Baratchi, Sara, Zhang, Chen, Kayani, Aminuddin A., Chrimes, Adam F., Nahavandi, Saeid, Wlodkowic, Donald, Mitchell, Arnan and Kalantar-zadeh, Kourosh 2011, Dielectrophoresis of micro/nano particles using curved microelectrodes, in SPIE 2011 : Proceedings of SPIE - The International Society for Optical Engineering, SPIE, Bellingham, Wash., pp. 1-9.

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Title Dielectrophoresis of micro/nano particles using curved microelectrodes
Author(s) Khoshmanesh, Khashayar
Tovar-Lopez, Francisco J.
Baratchi, Sara
Zhang, Chen
Kayani, Aminuddin A.
Chrimes, Adam F.
Nahavandi, SaeidORCID iD for Nahavandi, Saeid orcid.org/0000-0002-0360-5270
Wlodkowic, Donald
Mitchell, Arnan
Kalantar-zadeh, Kourosh
Conference name Smart Nano-Micro Materials and Devices. Conference (2011 : Hawthorn, Vic.)
Conference location Hawthorn, Vic.
Conference dates 5-7 Dec. 2011
Title of proceedings SPIE 2011 : Proceedings of SPIE - The International Society for Optical Engineering
Editor(s) Juodkazis, Saulius
Gu, Min
Publication date 2011
Conference series Smart Nano-Micro Materials and Devices Conference
Start page 1
End page 9
Total pages 9
Publisher SPIE
Place of publication Bellingham, Wash.
Keyword(s) biomedical applications
dead cells
DEP force
dielectrophoretic
entrance region
environmental scanning electron microscopy
experimental analysis
induced motions
lab-on-a-chip systems
micro fluidic system
micro/nano particle
microfluidic platforms
morphological properties
operating strategy
polystyrene particle
real time analysis
strong electric fields
trapping model
tumour cells
two parameter
unique features
Summary Dielectrophoresis, the induced motion of polarisable particles in non-homogenous electric field, has been proven as a versatile mechanism to transport, immobilise, sort and characterise micro/nano scale particle in microfluidic platforms. The performance of dielectrophoretic (DEP) systems depend on two parameters: the configuration of microelectrodes designed to produce the DEP force and the operating strategies devised to employ this force in such processes. This work summarises the unique features of curved microelectrodes for the DEP manipulation of target particles in microfluidic systems. The curved microelectrodes demonstrate exceptional capabilities including (i) creating strong electric fields over a large portion of their structure, (ii) minimising electro-thermal vortices and undesired disturbances at their tips, (iii) covering the entire width of the microchannel influencing all passing particles, and (iv) providing a large trapping area at their entrance region, as evidenced by extensive numerical and experimental analyses. These microelectrodes have been successfully applied for a variety of engineering and biomedical applications including (i) sorting and trapping model polystyrene particles based on their dimensions, (ii) patterning carbon nanotubes to trap low-conductive particles, (iii) sorting live and dead cells based on their dielectric properties, (iv) real-time analysis of drug-induced cell death, and (v) interfacing tumour cells with environmental scanning electron microscopy to study their morphological properties. The DEP systems based on curved microelectrodes have a great potential to be integrated with the future lab-on-a-chip systems.
Notes Reproduced with the kind permission of the copyright owner.
ISBN 9780819488459
ISSN 0277-786X
Language eng
Field of Research 091306 Microelectromechanical Systems (MEMS)
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category E1 Full written paper - refereed
Copyright notice ©2011, SPIE
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30044763

Document type: Conference Paper
Collections: Centre for Intelligent Systems Research
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.