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Thrombocytopenia in solid tumors

Khasraw, Mustafa, Faraj, Heewa and Sheikha, Anwar 2010, Thrombocytopenia in solid tumors, European journal of clinical and medical oncology, vol. 2, no. 2, pp. 89-92.

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Title Thrombocytopenia in solid tumors
Author(s) Khasraw, Mustafa
Faraj, Heewa
Sheikha, Anwar
Journal name European journal of clinical and medical oncology
Volume number 2
Issue number 2
Start page 89
End page 92
Total pages 4
Publisher San Lucas Medical Ltd.
Place of publication London, England
Publication date 2010-06
ISSN 1759-8958
1759-8966
Keyword(s) paraneoplastic immune thrombocytopenia
thrombotic thrombocytopenia
solid tumors
Summary Thrombocytopenia in patients with solid malignancy can be caused by bone marrow involvement or toxicity from anticancer therapy; however, it could rarely be the first presentation of a tumor such as breast cancer or lymphoma. Hematological paraneoplastic syndromes such as paraneoplastic thrombocytopenia and/or immune thrombocytopenic purpura (ITP) are well described as secondary findings simultaneously with malignancies such as breast cancer and lymphoma. Other hematological conditions such as severe amegakaryocytic thrombocytopenia, thrombotic thrombocytopenic purpura (TTP), and myelodysplastic syndromes (MDS) have also rarely been described as a possible paraneoplastic process complicating solid tumors. On the one hand, occult disseminated malignancy may mimic ITP and TTP, leading to diagnostic and therapeutic problems. On the other hand, thrombocytopenia could be the first manifestation of cancer.
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Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2010, San Lucas Medical
Persistent URL http://hdl.handle.net/10536/DRO/DU:30046484

Document type: Journal Article
Collections: School of Medicine
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.