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Neurological complication of systemic cancer

Khasraw, Mustafa and Posner, Jerome B. 2010, Neurological complication of systemic cancer, Lancet neurology, vol. 9, no. 12, pp. 1214-1227, doi: 10.1016/S1474-4422(10)70220-9.

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Title Neurological complication of systemic cancer
Author(s) Khasraw, MustafaORCID iD for Khasraw, Mustafa orcid.org/0000-0003-3249-9849
Posner, Jerome B.
Journal name Lancet neurology
Volume number 9
Issue number 12
Start page 1214
End page 1227
Total pages 14
Publisher The Lancet Publishing Group
Place of publication London, England
Publication date 2010-12
ISSN 1474-4422
1474-4465
Keyword(s) brain diseases
cognition disorders
humans
neoplasms
nervous system diseases
spinal cord diseases
Summary Neurological complications of systemic cancer—those arising outside the nervous system—can be distressing, disabling, and sometimes fatal. Diagnosis is often difficult because different neurological disorders may present with similar signs and symptoms. Furthermore, comorbid neurological illnesses, common in elderly patients with cancer, can complicate diagnosis. Early diagnosis and aggressive treatment can improve neurological symptoms and can substantially enhance a patient's quality of life. We approach the problem of neurological complications of systemic cancer as would a neurologist: first by identifying the anatomical area or areas that are affected (ie, brain, spinal cord, peripheral nerve), then by evaluating the diagnostic approach, considering the symptoms and signs and including appropriate laboratory tests, and finally, by recommending treatment. We focus on disorders that are difficult to diagnose, need neurological consultation, and for which effective treatments exist.
Language eng
DOI 10.1016/S1474-4422(10)70220-9
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2010, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30046494

Document type: Journal Article
Collection: School of Medicine
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