You are not logged in.

Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder

Malhi, Gin S., Bargh, Danielle M., McIntyre, Roger, Gitlin, Michael, Frye, Mark A., Bauer, Michael and Berk, Michael 2012, Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder, Bipolar disorders supplement, vol. 14, no. Supplement 2, Special issue : Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder, pp. 1-21, doi: 10.1111/j.1399-5618.2012.00989.x.

Attached Files
Name Description MIMEType Size Downloads

Title Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder
Author(s) Malhi, Gin S.
Bargh, Danielle M.
McIntyre, Roger
Gitlin, Michael
Frye, Mark A.
Bauer, Michael
Berk, MichaelORCID iD for Berk, Michael orcid.org/0000-0002-5554-6946
Journal name Bipolar disorders supplement
Volume number 14
Issue number Supplement 2
Season Special issue : Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder
Start page 1
End page 21
Total pages 21
Publisher Wiley - Blackwell Publishing
Place of publication Malden, Mass.
Publication date 2012-05
ISSN 1399-2406
1600-5511
Keyword(s) acute treatment
bipolar disorder
evidence-based review
guidelines
maintenance treatment
treatment
Summary Objective:  To provide practical and clinically meaningful treatment recommendations that amalgamate clinical experience and research findings for each phase of bipolar disorder.

Methods:  A comprehensive search of the literature was undertaken using electronic database search engines (Medline, PubMed, Cochrane reviews) using key words (e.g., bipolar depression, mania, treatment). All relevant randomised controlled trials were examined, along with review papers, meta-analyses, and book chapters known to the authors. In addition, the recommendations from accompanying papers in this supplement have been distilled and captured in the form of summary boxes. The findings, in conjunction with the clinical experience of international researchers and clinicians who are practiced in treating mood disorders, formed the basis of the treatment recommendations within this paper.

Results:  Balancing clinical experience with evidence informed and lead to the development of practical clinical recommendations that emphasise the importance of safety and tolerability alongside efficacy in the clinical management of bipolar disorder.

Conclusions:  The current paper summarises the treatment recommendations relating to each phase of bipolar disorder while providing additional, evidence-based, practical insights. Medication-related side effects and monitoring strategies highlight the importance of safety and tolerability considerations, which, along with efficacy information, should be given equal merit.
Language eng
DOI 10.1111/j.1399-5618.2012.00989.x
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2012, John Wiley and Sons A/S
Persistent URL http://hdl.handle.net/10536/DRO/DU:30047128

Document type: Journal Article
Collection: School of Medicine
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 21 times in TR Web of Science
Scopus Citation Count Cited 25 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 534 Abstract Views, 2 File Downloads  -  Detailed Statistics
Created: Tue, 14 Aug 2012, 10:39:30 EST by Jane Moschetti

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.