Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder

Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder

Malhi, Gin S., Bargh, Danielle M., McIntyre, Roger, Gitlin, Michael, Frye, Mark A., Bauer, Michael and Berk, Michael 2012, Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder, Bipolar disorders supplement, vol. 14, no. Supplement 2, Special issue : Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder, pp. 1-21.

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Title	Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder
Author(s)	Malhi, Gin S. Bargh, Danielle M. McIntyre, Roger Gitlin, Michael Frye, Mark A. Bauer, Michael Berk, Michael
Journal name	Bipolar disorders supplement
Volume number	14
Issue number	Supplement 2
Season	Special issue : Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder
Start page	1
End page	21
Total pages	21
Publisher	Wiley - Blackwell Publishing
Place of publication	Malden, Mass.
Publication date	2012-05
ISSN	1399-2406 1600-5511
Keyword(s)	acute treatment bipolar disorder evidence-based review guidelines maintenance treatment treatment
Summary	Objective: To provide practical and clinically meaningful treatment recommendations that amalgamate clinical experience and research findings for each phase of bipolar disorder. Methods: A comprehensive search of the literature was undertaken using electronic database search engines (Medline, PubMed, Cochrane reviews) using key words (e.g., bipolar depression, mania, treatment). All relevant randomised controlled trials were examined, along with review papers, meta-analyses, and book chapters known to the authors. In addition, the recommendations from accompanying papers in this supplement have been distilled and captured in the form of summary boxes. The findings, in conjunction with the clinical experience of international researchers and clinicians who are practiced in treating mood disorders, formed the basis of the treatment recommendations within this paper. Results: Balancing clinical experience with evidence informed and lead to the development of practical clinical recommendations that emphasise the importance of safety and tolerability alongside efficacy in the clinical management of bipolar disorder. Conclusions: The current paper summarises the treatment recommendations relating to each phase of bipolar disorder while providing additional, evidence-based, practical insights. Medication-related side effects and monitoring strategies highlight the importance of safety and tolerability considerations, which, along with efficacy information, should be given equal merit.
Language	eng
Field of Research	119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective	970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category	C1 Refereed article in a scholarly journal
Copyright notice	©2012, John Wiley and Sons A/S
Persistent URL	http://hdl.handle.net/10536/DRO/DU:30047128

Document type:	Journal Article
Collection:	School of Medicine

Citation counts:	Cited 7 times in TR Web of Science Cited 9 times in Scopus
Access Statistics:	13 Abstract Views, 1 File Downloads - Detailed Statistics
Created:	Tue, 14 Aug 2012, 10:39:30 EST by Jane Moschetti

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