Dimerization of retroviral RNA genomes : an inseparable pair Paillart, Jean-Christophe, Shehu-Xhilaga, Miranda, Marquet, Roland and Mak, Johnson 2004, Dimerization of retroviral RNA genomes : an inseparable pair, Nature reviews. Microbiology, vol. 2, no. 6, pp. 461-472, doi: 10.1038/nrmicro903. Attached Files Name Description MIMEType Size Downloads Title Dimerization of retroviral RNA genomes : an inseparable pair Author(s) Paillart, Jean-Christophe Shehu-Xhilaga, Miranda Marquet, Roland Mak, Johnson orcid.org/0000-0002-5229-5707 Journal name Nature reviews. Microbiology Volume number 2 Issue number 6 Start page 461 End page 472 Total pages 12 Publisher Nature Publishing Group Place of publication London, England Publication date 2004-06 ISSN 1740-1526 1740-1534 Keyword(s) base sequence dimerization genome viral HIV-1 models molecular molecular sequence data nucleic acid conformation virus replication Summary Many viruses carry more than one segment of nucleic acid into the virion particle, but retroviruses are the only known group of viruses that contain two identical (or nearly identical) copies of the RNA genome within the virion. These RNA genomes are non-covalently joined together through a process known as genomic RNA dimerization. Uniquely, the RNA dimerization of the retroviral genome is of crucial importance for efficient retroviral replication. In this article, our current understanding of the relationship between retroviral genome conformation, dimerization and replication is reviewed. Language eng DOI 10.1038/nrmicro903 Field of Research 119999 Medical and Health Sciences not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2004, Nature Publishing Group Persistent URL http://hdl.handle.net/10536/DRO/DU:30047554 Document type: Journal Article Collection: School of Medicine Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Thu, 30 Aug 2012, 09:42:27 EST Thu, 30 Aug 2012, 10:38:48 EST Wed, 19 Sep 2012, 11:39:41 EST Wed, 19 Sep 2012, 11:41:07 EST Tue, 15 Apr 2014, 14:27:04 EST Filtered Full Citation counts:   Cited 190 times in TR Web of Science Cited 199 times in Scopus Search Google Scholar Access Statistics: 217 Abstract Views, 2 File Downloads  -  Detailed Statistics Created: Thu, 30 Aug 2012, 09:42:27 EST

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