The relationship between coronary heart disease (CHD) and major depressive disorder (MDD) :  key mechanisms and the role of quality of life

O'Neil, A. 2013, The relationship between coronary heart disease (CHD) and major depressive disorder (MDD) :  key mechanisms and the role of quality of life, Europe's journal of psychology, vol. 9, no. 1, pp. 163-184.

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Title The relationship between coronary heart disease (CHD) and major depressive disorder (MDD) :  key mechanisms and the role of quality of life
Author(s) O'Neil, A.
Journal name Europe's journal of psychology
Volume number 9
Issue number 1
Start page 163
End page 184
Total pages 22
Publisher Universitatea din Bucuresti, Asociatia Studentilor
Place of publication Bucharest, Romania
Publication date 2013
ISSN 1841-0413
Keyword(s) coronary heart disease
cardiovascular disease
mechanisms
vocational functioning
health related quality of life
depression
Summary Various trials have been conducted evaluating depression management programs for patients with Coronary Heart Disease (CHD). However, to date, the most effective way to manage this co-morbidity in the real world setting remains unclear. To better understand the past successes and failures of previous trials and subsequently develop suitable interventions that target key components of health related quality of life (HRQOL) such as mental, physical and vocational functioning, we first need to understand the mechanisms underpinning the relationship between the two conditions. This paper will draw on the key literature in this field as identified by psychiatric, medical and social sciences databases (Cochrane Central Register of Controlled Trials, PubMed, OVID, Medline) available up to January 2012, with the aim to conduct a narrative review which explores: the aetiological relationship between depression and CHD; its association with HRQOL; the relationship between CHD, depression and vocational functioning; and the impact of depression treatment on these outcomes. Key recommendations are made regarding the management of this prevalent co-morbidity in clinical settings.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30047639

Document type: Journal Article
Collection: School of Medicine
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