Zinc for treating of children and adolescents with attention-deficit hyperactivity disorder : a systematic review of randomized controlled clinical trials

Ghanizadeh, A. and Berk, M. 2012, Zinc for treating of children and adolescents with attention-deficit hyperactivity disorder : a systematic review of randomized controlled clinical trials, European journal of clinical nutrition, vol. 67, no. 1, pp. 122-124.

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Title Zinc for treating of children and adolescents with attention-deficit hyperactivity disorder : a systematic review of randomized controlled clinical trials
Author(s) Ghanizadeh, A.
Berk, M.
Journal name European journal of clinical nutrition
Volume number 67
Issue number 1
Start page 122
End page 124
Total pages 3
Publisher Nature Publishing Group
Place of publication London, England
Publication date 2012-01
ISSN 0954-3007
1476-5640
Keyword(s) attention-deficit hyperactivity disorder
zinc
psychotropic
treatment
nutrition
children
Summary This study systematically reviews the randomized clinical trials examining the effect of zinc on attention-deficit hyperactivity disorder (ADHD), searching the PubMed/Medline and Scholar Google databases. All randomized controlled trials that examined zinc as the intervention, and ADHD as the primary outcome were included. Only three randomized controlled trials, one which included a community sample and two that included clinical samples, met inclusion criteria. The only trial that was well controlled and randomized according to the baseline zinc level showed that using zinc, either alone or in combination with stimulants, did not improve ADHD. Considering the lack of clear evidence for the effect of zinc on ADHD and the possible effect of zinc on the nervous system, more clinical studies are needed to prove or disprove the effect of zinc as a monotherapy or adjuvant therapy.
Language eng
Field of Research 110299 Cardiovascular Medicine and Haematology not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30050301

Document type: Journal Article
Collection: School of Medicine
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