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Co-prescription of medication for bipolar disorder and diabetes mellitus : a nationwide population based study with focus on gender differences Svendal, Gjertrud, Fasmer, Ole Bernt, Engeland, Anders, Berk, Michael and Lund, Anders 2012, Co-prescription of medication for bipolar disorder and diabetes mellitus : a nationwide population based study with focus on gender differences, BMC medicine, vol. 10, Article number148, pp. 1-6. Attached Files Name Description MIMEType Size Downloads berk-coprescriptionof-2012.pdf Published version application/pdf 120.39KB 7 Title Co-prescription of medication for bipolar disorder and diabetes mellitus : a nationwide population based study with focus on gender differences Author(s) Svendal, Gjertrud Fasmer, Ole Bernt Engeland, Anders Berk, Michael Lund, Anders Journal name BMC medicine Volume number 10 Season Article number148 Start page 1 End page 6 Total pages 6 Publisher BioMed Central Place of publication England, London Publication date 2012 ISSN 1741-7015 Keyword(s) bipolar disorder diabetes mellitus gender Summary Background Studies have shown a correlation between bipolar disorder and diabetes mellitus. It is unclear if this correlation is a part of common pathophysiological pathways, or if medication for bipolar disorder has negative effects on blood sugar regulation. Methods The Norwegian prescription database was analyzed. Prescriptions for lithium, lamotrigine, carbamazepine and valproate were used as proxies for bipolar disorder. Prescriptions for insulin and oral anti-diabetic agents were used as proxies for diabetes mellitus. We explored the association between medication for bipolar disorder and diabetes medication by logistic regression Results We found a strong association between concomitant use of medication to treat diabetes mellitus and mood stabilizers for the treatment of bipolar disorder. Females had a 30% higher risk compared to men of being treated for both disorders. Persons using oral anti-diabetic agents had higher odds of receiving valproate than either lithium or lamotrigine. Use of insulin as monotherapy seemed to have lower odds than oral anti-diabetic agents of co-prescription of mood stabilizers, compared to the general population. Conclusions This study showed a strong association between the use of mood stabilizers and anti-diabetic agents. The association was stronger among women than men. Language eng Field of Research 119999 Medical and Health Sciences not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2012, BioMed Central Persistent URL http://hdl.handle.net/10536/DRO/DU:30050626 Document type: Journal Article Collections: School of Medicine Open Access Collection Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Mon, 18 Feb 2013, 10:44:49 EST Mon, 18 Feb 2013, 10:51:39 EST Wed, 27 Feb 2013, 13:27:40 EST Wed, 27 Feb 2013, 13:28:35 EST Tue, 24 Sep 2013, 09:47:55 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Search Google Scholar Access Statistics: 80 Abstract Views, 7 File Downloads  -  Detailed Statistics Created: Mon, 18 Feb 2013, 10:44:48 EST by Jane Moschetti

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.