Insulin sensitivity not modulated 24 to 78 h after acute resistance exercise in type 2 diabetes patients

Gordon, B. A., Fraser, S. F., Bird, S. R. and Benson, A. C. 2013, Insulin sensitivity not modulated 24 to 78 h after acute resistance exercise in type 2 diabetes patients, Diabetes, obesity and metabolism, vol. 15, no. 5, pp. 478-480.

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Title Insulin sensitivity not modulated 24 to 78 h after acute resistance exercise in type 2 diabetes patients
Author(s) Gordon, B. A.
Fraser, S. F.
Bird, S. R.
Benson, A. C.
Journal name Diabetes, obesity and metabolism
Volume number 15
Issue number 5
Start page 478
End page 480
Total pages 3
Publisher Blackwell Publishing
Place of publication London, England
Publication date 2013-05
ISSN 1462-8902
1463-1326
Keyword(s) critical care
sepsis
necrotizing fasciitis
Summary Background
The aim of this study was to describe the clinical characteristics, causative pathogens, clinical management and outcomes of patients presenting to a tertiary adult Australian intensive care unit (ICU) with a diagnosis of necrotizing fasciitis (NF).
Methods
This retrospective observational study was conducted in a 19-bed, level III, adult ICU in a 450-bed tertiary, regional hospital. Clinical databases were accessed for patients diagnosed with NF and admitted to The Geelong Hospital ICU between 1 February 2000 and 1 June 2011. Information on severity of sepsis, surgical procedures and microbiological results were collected.
Results
Twenty patients with NF were identified. The median age was 52.5 years and 38% were female. The overall mortality rate was 8.3%. Common co-morbidities were diabetes (21%) and heart failure (17%), although 50% of patients had no co-morbidities. Group A Streptococcus was the identified pathogen in 11 (46%) patients, and Streptococcus milleri group in 5 (21%) patients. Hyperbaric oxygen therapy was not used in the majority of patients. The initial antibiotics administered were active against subsequently cultured bacteria in 83% of patients. Median time to surgical debridement was 20 h. Diagnosis and management was delayed in the nosocomial group.
Conclusions
This study reports physiological data, aetiology and therapeutic interventions in NF for an adult tertiary hospital. We demonstrate one of the lowest reported mortality rates, with early surgical debridement being achieved in the majority of patients. The main delay was found to be in the diagnosis of NF.
Language eng
Field of Research 110602 Exercise Physiology
Socio Economic Objective 920104 Diabetes
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30050828

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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Created: Mon, 25 Feb 2013, 20:33:46 EST by Steve Fraser

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