Frequency of excisions and yields of malignant skin tumors in a population-based screening intervention of 360 288 whole-body examinations

Waldmann, Annika, Nolte, Sandra, Geller, Alan C., Katalinic, Alexander, Weinstock, Martin A., Volkmer, Beate, Greinert, Ruediger and Breitbar, Eckhard W. 2012, Frequency of excisions and yields of malignant skin tumors in a population-based screening intervention of 360 288 whole-body examinations, JAMA dermatology, vol. 148, no. 8, pp. 903-910.

Attached Files
Name Description MIMEType Size Downloads

Title Frequency of excisions and yields of malignant skin tumors in a population-based screening intervention of 360 288 whole-body examinations
Author(s) Waldmann, Annika
Nolte, Sandra
Geller, Alan C.
Katalinic, Alexander
Weinstock, Martin A.
Volkmer, Beate
Greinert, Ruediger
Breitbar, Eckhard W.
Journal name JAMA dermatology
Volume number 148
Issue number 8
Start page 903
End page 910
Total pages 8
Publisher American Medical Association
Place of publication Chicago, Ill.
Publication date 2012-08
ISSN 2168-6068
0003-987X
Keyword(s) skin cancer
excisions
tumors
Summary Objective To explore the frequency of excisions and yields of histopathologically confirmed skin cancer.

Design A population-based skin cancer screening intervention (the SCREEN project) in the German state of Schleswig-Holstein (July 1, 2003, to June 30, 2004).

Setting Physician offices. Participants could choose between nondermatologist physicians and dermatologists for their initial whole-body skin examination. All screening physicians received a mandatory 8-hour training course.

Participants Inhabitants of Schleswig-Holstein 20 years or older with statutory health insurance (N = 360 288).

Main Outcome Measures
Frequency of excisions and yields of malignant skin tumors (malignant melanomas [MMs], basal cell carcinomas [BCCs], and squamous cell carcinomas [SCCs]), stratified by sex and age.

Results Overall, 15 983 excisions were performed (1 of 23 screenees). A total of 3103 malignant skin tumors were diagnosed in 2911 persons: 585 MMs, 1961 BCCs, 392 SCCs, and 165 other malignant skin tumors. Overall, 116 persons (3103 of 360 288) had to be screened to find 1 malignant tumor, with 1 of 620 for MM, 1 of 184 for BCC, and 1 of 920 for SCC. Twenty excisions were performed to find 1 melanoma in men 65 years and older, but more than 50 excisions were required to find 1 melanoma in men aged between 20 and 49 years.

Conclusions The results of SCREEN suggest a high yield of malignant skin tumors in a large-scale population-based screening project. We found that a high number of excisions was performed in the youngest screenees with an associated low yield, suggesting a need in screener training to emphasize a more conservative attitude toward excisions in young screenees.
Notes JAMA Dermatology formerly Archives of Dermatology
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30053047

Document type: Journal Article
Collection: School of Health and Social Development
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 6 times in TR Web of Science
Scopus Citation Count Cited 5 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 34 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Thu, 20 Jun 2013, 14:59:17 EST by Jane Moschetti

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.