Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation

Yatmaz, S., Seow, H.J., Gualano, R.C., Wong, Z.X., Stambas, J., Selemidis, S., Crack, P.J., Bozinovski, S., Anderson, G.P. and Vlahos, R. 2013, Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation, American journal of respiratory cell and molecular biology, vol. 48, no. 1, pp. 17-26.

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Title Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation
Author(s) Yatmaz, S.
Seow, H.J.
Gualano, R.C.
Wong, Z.X.
Stambas, J.
Selemidis, S.
Crack, P.J.
Bozinovski, S.
Anderson, G.P.
Vlahos, R.
Journal name American journal of respiratory cell and molecular biology
Volume number 48
Issue number 1
Start page 17
End page 26
Total pages 10
Publisher American Thoracic Society
Place of publication New York, N.Y.
Publication date 2013-01
ISSN 1044-1549
Keyword(s) oxidative stress
reactive oxygen species
hydrogen peroxide
HKx31
ebselen
antioxidants
Summary Oxidative stress caused by excessive reactive oxygen species production is implicated in influenza A virus–induced lung disease. Glutathione peroxidase (GPx)-1 is an antioxidant enzyme that may protect lungs from  such damage. The objective of this study was to determine if GPx-1 protects the lung against influenza A virus–induced lung inflammation in vivo.
Language eng
Field of Research 110203 - Respiratory Diseases
110309 - Infectious Diseases
Socio Economic Objective 920109 - Infectious Diseases
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30053437

Document type: Journal Article
Collection: School of Medicine
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Created: Thu, 04 Jul 2013, 12:48:35 EST by John Stambas

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