Fundamentals and applications of Maldi-Tof MS

Goyal, Arshi, Jain, Yachna, Verma, Madan Lal and Jana, Asim Kumar 2010, Fundamentals and applications of Maldi-Tof MS, in BEATS 2010 : Proceedings of the 2010 International Conference on Biomedical Engineering and Assistive Technologies, Jalandhar, India, BEATS, Jalandhar, India, pp. 1-4.

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Title Fundamentals and applications of Maldi-Tof MS
Author(s) Goyal, Arshi
Jain, Yachna
Verma, Madan Lal
Jana, Asim Kumar
Conference name Biomedical Engineering and Assistive Technologies. Conference (2010 : Jalandhar, India)
Conference location Jalandhar, India
Conference dates 17-19 Dec. 2010
Title of proceedings BEATS 2010 : Proceedings of the 2010 International Conference on Biomedical Engineering and Assistive Technologies, Jalandhar, India
Editor(s) [Unknown]
Publication date 2010
Conference series Biomedical Engineering and Assistive Technologies Conference
Start page 1
End page 4
Total pages 4
Publisher BEATS
Place of publication Jalandhar, India
Keyword(s) maldi-tof
applications
Summary MALDI was developed for the ionisation of relatively large polypeptides and proteins but its application has widened to incorporate glycoproteins, oligonucleotides and complex carbohydrates. A great advantage of MALDI TOF MS is that the process of soft-ionisation causes little or no fragmentation of analytes, allowing the molecular ions of analytes to be identified, even within mixtures. MALDI TOF MS analysis is sensitive and very rapid as once the sample has been mixed with a 'matrix' on a MALDI target, a spectrum can be generated within seconds. Hence, the majority of protein and oligonucleotide analysis in the context of high throughput proteomics and genomics is carried out by MALDI TOF mass spectrometry.
Language eng
Field of Research 100301 Biocatalysis and Enzyme Technology
100306 Industrial Molecular Engineering of Nucleic Acids and Proteins
100703 Nanobiotechnology
Socio Economic Objective 860106 Oils and Fats (incl. Margarines)
HERDC Research category E1.1 Full written paper - refereed
Persistent URL http://hdl.handle.net/10536/DRO/DU:30054177

Document type: Conference Paper
Collection: School of Life and Environmental Sciences
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