The role of nanomedicine in cell based therapeutics in cancer and inflammation.

Samarasinghe, Rasika M, Kanwar, Rupinder K and Kanwar, Jagat R 2012, The role of nanomedicine in cell based therapeutics in cancer and inflammation., International journal of molecular and cellular medicine, vol. 1, no. 3, Summer, pp. 133-144.

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Title The role of nanomedicine in cell based therapeutics in cancer and inflammation.
Author(s) Samarasinghe, Rasika M
Kanwar, Rupinder K
Kanwar, Jagat R
Journal name International journal of molecular and cellular medicine
Volume number 1
Issue number 3
Season Summer
Start page 133
End page 144
Total pages 12
Publisher Babol University of Medical Sciences
Place of publication Babol, Iran
Publication date 2012
ISSN 2251-9637
2251-9645
Keyword(s) nanomedicine
cell therapy
cancer
blood brain barrier
inflammation
Summary Cell based therapeutics is one of the most rapidly advancing medical fields, bringing together a range of fields including transplantation, tissue engineering and regeneration, biomaterials and stem cell biology. However, traditional cell-based therapeutics have many limitations, one of which is their harmful effects exhibited on healthy body cells due to their lack of specificity. Nanomedicine is providing an alternative treatment strategy that is more targeted and specific to a range of diseases. Varying from polymers conjugated with drugs or tissue targeting molecules, to proteins encapsulated within a polymer shell, nanomedicine will without a doubt play a major role in designing effective cell-based therapeutics that can overcome certain classical problems. These may include from addressing the problem of non-specificity of contemporary treatments to overcoming mechanical barriers, such as crossing cell membranes. This review summarises the recent work on nano-based cell therapy as a regenerative agent and as a therapeutic for cancer and neurological diseases.
Language eng
Field of Research 100701 Environmental Nanotechnology
111201 Cancer Cell Biology
110904 Neurology and Neuromuscular Diseases
Socio Economic Objective 920102 Cancer and Related Disorders
HERDC Research category C1.1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30054669

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