Nano-lactoferrin in diagnostic, imaging and targeted delivery for cancer and infectious diseases
Kanwar, Jagat R., Samarasinghe, Rasika M., Sehgal, Rakesh and Kanwar, Rupinder K. 2012, Nano-lactoferrin in diagnostic, imaging and targeted delivery for cancer and infectious diseases, Journal of cancer science & therapy, vol. 4, no. 3, pp. 31-42.
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Lactoferrin (Lf) is a natural occurring iron binding protein present in many mammalian excretions and involved in various physiological processes. Lf is used in the transport of iron along with other molecules and ions from the digestive system. However its the modulatory functions exhibited by Lf in connection to immune response, disease regression and diagnosis that has made this protein an attractive therapeutic against chronic diseases. Further, the exciting potentials of employing nanotechnology in advancing drug delivery systems, active disease targeting and prognosis have also shown some encouraging outcomes. This review focuses on the role of Lf in diagnosing infection, cancer, neurological and inflammatory diseases and the recent nanotechnology based strategies.
Field of Research
110106 Medical Biochemistry: Proteins and Peptides (incl Medical Proteomics) 100701 Environmental Nanotechnology 111201 Cancer Cell Biology
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