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Silencing host genes using RNAi to impact virus growth in vitro

Birrer, Katherine 2012, Silencing host genes using RNAi to impact virus growth in vitro, MAppSc. thesis, School of Medicine, Deakin University.

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Title Silencing host genes using RNAi to impact virus growth in vitro
Author Birrer, Katherine
Institution Deakin University
School School of Medicine
Faculty Faculty of Health
Degree name MAppSc.
Date submitted 2012-11-21
Keyword(s) gene silencing
rna interference
avian influenza
Summary Using short interfering RNAs to silence individual human host genes we were able to demonstrate that alpha coatamer protein (COPA) is important for the replication of highly pathogenic Avian Influenza A/chicken/Vietnam/008/2004 H5N1 in vitro and may therefore hold potential as a target for novel antiviral therapeutics.
Language eng
Field of Research 110702 Applied Immunology (incl Antibody Engineering, Xenotransplantation and T-cell Therapies)
Socio Economic Objective 920109 Infectious Diseases
Description of original 177 p.
Copyright notice ┬ęThe author
Persistent URL http://hdl.handle.net/10536/DRO/DU:30056566

Document type: Thesis
Collections: Higher degree theses (full text)
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.