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Salivary immunoglobulin A (sIgA) as a biomarker of immune suppression following the combat fitness assessment

Pacque, P. F., Booth, C. K. and Dwyer, D. B. 2002, Salivary immunoglobulin A (sIgA) as a biomarker of immune suppression following the combat fitness assessment, Defence Science and Technology Organisation, Melbourne, Vic..

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Title Salivary immunoglobulin A (sIgA) as a biomarker of immune suppression following the combat fitness assessment
Author(s) Pacque, P. F.
Booth, C. K.
Dwyer, D. B.
Publication date 2002-05
Issue number Article: DSTO-RR-0236
Total pages 54
Publisher Defence Science and Technology Organisation
Place of publication Melbourne, Vic.
Summary SIgA is a potential biomarker for stress. The usual day-to-day and within day variation in sIgA amongst a group of healthy Army reservists was estimated and the acute response of sIgA to moderate intensity exercise (Combat Fitness Assessment) undertaken in both cool-dry and hot-humid conditions was determined. The results indicate that thermal and cardiovascular strain resulting from moderate intensity exercise in hot-humid conditions suppresses sIgA for at least 24 hours post-exercise. Salivary sIgA exhibits a wide biological variation which casts some doubt on its usefulness as a biomarker, however because sIgA has been shown to be sensitive to dietary restriction, alcohol consumption, loss of body mass, fatigue and negative emotions in previous studies and now heat-induced cardiovascular strain, further work is warranted to develop this biomarker.
Language eng
Field of Research 110602 Exercise Physiology
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category A6.1 Research report/technical paper
Copyright notice ©2002, Defence Science and Technology Organisation
Persistent URL http://hdl.handle.net/10536/DRO/DU:30058766

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Created: Thu, 05 Dec 2013, 10:50:36 EST by Dan Dwyer

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.