Formulation and simulation of a 3D mechanical model of embryos for microinjection Asgari, Marzieh, Abdi, Hamid, Lim, Chee Peng and Nahavandi, Saeid 2013, Formulation and simulation of a 3D mechanical model of embryos for microinjection, in SMC 2013 : Proceedings of the 2013 IEEE International Conference on Systems, Man and Cybernetics, IEEE, Piscataway, N.J., pp. 2219-2224. Attached Files Name Description MIMEType Size Downloads Title Formulation and simulation of a 3D mechanical model of embryos for microinjection Author(s) Asgari, Marzieh orcid.org/0000-0001-7183-7156 Abdi, Hamid orcid.org/0000-0001-6597-7136 Lim, Chee Peng orcid.org/0000-0003-4191-9083 Nahavandi, Saeid orcid.org/0000-0002-0360-5270 Conference name IEEE Systems, Man and Cybernetics. Conference (2013 : Manchester, England) Conference location Manchester, England Conference dates 13-16 Oct. 2013 Title of proceedings SMC 2013 : Proceedings of the 2013 IEEE International Conference on Systems, Man and Cybernetics Editor(s) [Unknown] Publication date 2013 Conference series IEEE Systems, Man and Cybernetics Conference Start page 2219 End page 2224 Total pages 6 Publisher IEEE Place of publication Piscataway, N.J. Keyword(s) component cell modelling indentation force and deformation zebrafish egg microinjection Summary The understanding of cell manipulation, for example in microinjection, requires an accurate model of the cells. Motivated by this important requirement, a 3D particlebased mechanical model is derived for simulating the deformation of the fish egg membrane and the corresponding cellular forces during microrobotic cell injection. The model is formulated based on the kinematic and dynamic of spring- damper configuration with multi-particle joints considering the visco-elastic fluidic properties. It simulates the indentation force feedback as well as cell visual deformation during microinjection. A preliminary simulation study is conducted with different parameter configurations. The results indicate that the proposed particle-based model is able to provide similar deformation profiles as observed from a real microinjection experiment of the zebrafish embryo published in the literature. As a generic modelling approach is adopted, the proposed model also has the potential in applications with different types of manipulation such as micropipette cell aspiration. Language eng Field of Research 091307 Numerical Modelling and Mechanical Characterisation Socio Economic Objective 970109 Expanding Knowledge in Engineering HERDC Research category E1 Full written paper - refereed Copyright notice ©2013, IEEE Persistent URL http://hdl.handle.net/10536/DRO/DU:30058836 Document type: Conference Paper Collections: Institute for Intelligent Systems Research and Innovation (IISRI) GTP Research   Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 09 Dec 2013, 10:49:52 EST Mon, 09 Dec 2013, 13:20:06 EST Tue, 10 Dec 2013, 14:51:57 EST Mon, 17 Feb 2014, 15:41:16 EST Tue, 18 Feb 2014, 08:47:33 EST Wed, 02 Jul 2014, 16:47:59 EST Mon, 11 Aug 2014, 10:31:57 EST Fri, 22 Aug 2014, 16:16:41 EST Wed, 21 Oct 2015, 14:56:52 EST Wed, 21 Oct 2015, 18:40:00 EST Filtered Full Citation counts:   Cited 2 times in TR Web of Science Cited 4 times in Scopus Search Google Scholar Access Statistics: 641 Abstract Views, 3 File Downloads  -  Detailed Statistics Created: Mon, 09 Dec 2013, 10:49:52 EST

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