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Evolution of the JAK-STAT pathway

Liongue, Clifford and Ward, Alister 2013, Evolution of the JAK-STAT pathway, JAK-STAT, vol. 2, no. 1, pp. e22756-1-e22756-8, doi: 10.4161/jkst.22756.

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Title Evolution of the JAK-STAT pathway
Author(s) Liongue, CliffordORCID iD for Liongue, Clifford
Ward, AlisterORCID iD for Ward, Alister
Journal name JAK-STAT
Volume number 2
Issue number 1
Start page e22756-1
End page e22756-8
Total pages 8
Publisher Landes Bioscience
Place of publication Austin, Tex.
Publication date 2013
ISSN 2162-3996
Keyword(s) JAK
Summary The JAK-STAT pathway represents a finely tuned orchestra capable of rapidly facilitating an exquisite symphony of responses from a complex array of extracellular signals. This review explores the evolution of the JAK-STAT pathway: the origins of the individual domains from which it is constructed, the formation of individual components from these basic building blocks, the assembly of the components into a functional pathway, and the subsequent reiteration of this basic template to fulfill a variety of roles downstream of cytokine receptors.
Language eng
DOI 10.4161/jkst.22756
Field of Research 060111 Signal Transduction
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2013, Landes Bioscience
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Document type: Journal Article
Collection: School of Medicine
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