The association of cycling with all-cause, cardiovascular and cancer mortality: findings from the population-based EPIC-Norfolk cohort

Sahlqvist, Shannon, Goodman, Anna, Simmons, Rebecca K., Khaw, Kay-Tee, Cavill, Nick, Foster, Charlie, Luben, Robert, Wareham, Nicholas J. and Ogilvie, David 2013, The association of cycling with all-cause, cardiovascular and cancer mortality: findings from the population-based EPIC-Norfolk cohort, BMJ Open, vol. 3, no. 11, pp. 1-10.

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Title The association of cycling with all-cause, cardiovascular and cancer mortality: findings from the population-based EPIC-Norfolk cohort
Author(s) Sahlqvist, Shannon
Goodman, Anna
Simmons, Rebecca K.
Khaw, Kay-Tee
Cavill, Nick
Foster, Charlie
Luben, Robert
Wareham, Nicholas J.
Ogilvie, David
Journal name BMJ Open
Volume number 3
Issue number 11
Start page 1
End page 10
Total pages 10
Publisher BMJ Group
Place of publication London, England
Publication date 2013
ISSN 2044-6055
Keyword(s) Cycling
Cardiovascular mortality
Cancer mortality
Population-based
EPIC-Norfolk cohort
Summary Objectives
To investigate associations between modest levels of total and domain-specific (commuting, other utility, recreational) cycling and mortality from all causes, cardiovascular disease and cancer.

Design
Population-based cohort study (European Prospective Investigation into Cancer and Nutrition study-Norfolk).

Setting
Participants were recruited from general practices in the east of England and attended health examinations between 1993 and 1997 and again between 1998 and 2000. At the first health assessment, participants reported their average weekly duration of cycling for all purposes using a simple measure of physical activity. At the second health assessment, participants reported a more detailed breakdown of their weekly cycling behaviour using the EPAQ2 physical activity questionnaire.

Participants
Adults aged 40–79 years at the first health assessment.

Primary outcome measure
All participants were followed for mortality (all-cause, cardiovascular and cancer) until March 2011.

Results
There were 22 450 participants with complete data at the first health assessment, of whom 4398 died during follow-up; and 13 346 participants with complete data at the second health assessment, of whom 1670 died during follow-up. Preliminary analyses using exposure data from the first health assessment showed that cycling for at least 60 min/week in total was associated with a 9% reduced risk of all-cause mortality (adjusted HR 0.91, 95% CI 0.84 to 0.99). Using the more precise measures of cycling available from the second health assessment, all types of cycling were associated with greater total moderate-to-vigorous physical activity; however, there was little evidence of an association between overall or domain-specific cycling and mortality.

Conclusions
Cycling, in particular for utility purposes, was associated with greater moderate-to-vigorous and total physical activity. While this study provides tentative evidence that modest levels of cycling may reduce the risk of mortality, further research is required to confirm how much cycling is sufficient to induce health benefits.
Language eng
Field of Research 110699 Human Movement and Sports Science not elsewhere classified
Socio Economic Objective 920401 Behaviour and Health
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2013, B M J Group
Persistent URL http://hdl.handle.net/10536/DRO/DU:30059657

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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