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A global approach to dissecting lipid-induced impairment of liver gluconeogenesis

Hayward, Bradley 2013, A global approach to dissecting lipid-induced impairment of liver gluconeogenesis, Ph.D. thesis, School of Medicine, Deakin University.

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Title A global approach to dissecting lipid-induced impairment of liver gluconeogenesis
Author Hayward, Bradley
Institution Deakin University
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name Ph.D.
Thesis advisor Walder, Ken
Konstantopoulos, Nicky
Molero, Juan Carlos
Jowett, Jeremy
Date submitted 2013-03
Keyword(s) Cholesterol metabolism
Lipids
Diabetes, Type 2
Summary This thesis identified: 1) novel aspects of cholesterol metabolism, 2) a novel signalling lipid in the phosphatidylinositol class, and 3) a gene involved in regulating lipid breakdown, as being regulated in the reversal of a fatty acid induced diabetic liver. The identification of these targets may allow for future development of targeted therapies against type 2 diabetes with a specific focus on the liver.
Language eng
Field of Research 111601 Cell Physiology
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
Description of original xxiii, 268 pages : diagrams, graphs, tables, some coloured
Copyright notice ┬ęThe author
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30060371

Document type: Thesis
Collections: Higher degree theses (full text)
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Created: Wed, 12 Feb 2014, 10:39:46 EST by Ana Esposo

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.