Synthesis and characterization of surface-enhanced Raman-scattered gold nanoparticles Kalmodia, Sushma, Harjwani, Jaidev, Rajeswari, Raguraman, Yang, Wenrong, Barrow, Colin J., Ramaprabhu, Sundara, Krishnakumar, Subramanian and Elchuri, Sailaja V. 2013, Synthesis and characterization of surface-enhanced Raman-scattered gold nanoparticles, International journal of nanomedicine, vol. 8, no. 1, pp. 4327-4338, doi: 10.2147/IJN.S49447. Attached Files Name Description MIMEType Size Downloads kalmodia-synthesisand-2013.pdf Published version application/pdf 1.22MB 120 Title Synthesis and characterization of surface-enhanced Raman-scattered gold nanoparticles Author(s) Kalmodia, Sushma Harjwani, Jaidev Rajeswari, Raguraman Yang, Wenrong orcid.org/0000-0001-8815-1951 Barrow, Colin J. orcid.org/0000-0002-2153-7267 Ramaprabhu, Sundara Krishnakumar, Subramanian Elchuri, Sailaja V. Journal name International journal of nanomedicine Volume number 8 Issue number 1 Start page 4327 End page 4338 Total pages 12 Publisher Dove Medical Press Place of publication Auckland, New Zealand Publication date 2013-11 ISSN 1178-2013 Keyword(s) GNPs SERS SPR stability Vitis vinifera L. Summary In this paper, we report a simple, rapid, and robust method to synthesize surface-enhanced Raman-scattered gold nanoparticles (GNPs) based on green chemistry. Vitis vinifera L. extract was used to synthesize noncytotoxic Raman-active GNPs. These GNPs were characterized by ultraviolet-visible spectroscopy, dynamic light-scattering, Fourier-transform infrared (FTIR), transmission electron microscopy (TEM), X-ray diffraction (XRD), and Raman spectroscopy. The characteristic surface plasmon-resonance band at ~528 nm is indicative of spherical particles, and this was confirmed by TEM. The N–H and C–O stretches in FTIR spectroscopy indicated the presence of protein molecules. The predominant XRD plane at (111) and (200) indicated the crystalline nature and purity of GNPs. GNPs were stable in the buffers used for biological studies, and exhibited no cytotoxicity in noncancerous MIO-M1 (Müller glial) and MDA-MB-453 (breast cancer) cell lines. The GNPs exhibited Raman spectral peaks at 570, 788, and 1,102 cm-1. These new GNPs have potential applications in cancer diagnosis, therapy, and ultrasensitive biomarker detection. Language eng DOI 10.2147/IJN.S49447 Field of Research 059999 Environmental Sciences not elsewhere classified Socio Economic Objective 970105 Expanding Knowledge in the Environmental Sciences HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2013, Dove Medical Press Free to Read? Yes Use Rights Persistent URL http://hdl.handle.net/10536/DRO/DU:30060968 Document type: Journal Article Collections: School of Life and Environmental Sciences Open Access Collection Centre for Biotechnology, Chemistry and Systems Biology Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Fri, 21 Feb 2014, 09:27:33 EST Thu, 27 Feb 2014, 08:02:24 EST Wed, 26 Mar 2014, 14:16:25 EST Wed, 21 Oct 2015, 19:06:27 EST Wed, 18 Nov 2015, 07:49:58 EST Fri, 26 Aug 2016, 15:12:46 EST Mon, 05 Sep 2016, 16:00:02 EST Tue, 06 Sep 2016, 23:02:45 EST Filtered Full Citation counts:   Cited 12 times in TR Web of Science Cited 14 times in Scopus Search Google Scholar Access Statistics: 339 Abstract Views, 115 File Downloads  -  Detailed Statistics Created: Fri, 21 Feb 2014, 09:27:33 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.