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Synthesis of flavonoids and flavonoid-based designed multiple ligands for hypertension

Thornton, Megan Tamara 2013, Synthesis of flavonoids and flavonoid-based designed multiple ligands for hypertension, Ph.D thesis, School of Life and Environmental Sciences, Deakin University.

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Title Synthesis of flavonoids and flavonoid-based designed multiple ligands for hypertension
Author Thornton, Megan Tamara
Institution Deakin University
School School of Life and Environmental Sciences
Faculty Faculty of Science, Engineering and Built Environment
Degree type Research doctorate
Degree name Ph.D
Thesis advisor Pfeffer, Fred
Henderson, Luke
Date submitted 2013-01
Keyword(s) Flavonoids compounds
Hypertension, Treatment of
Antioxidant
Antihypertensive
Therapeutic evaluation
Summary The flavonoids, a family of compounds found in nature, possess a wealth of established health benefits. In this research, a library of novel flavonoid compounds was synthesised for therapeutic evaluation. A particular focus was the attachment of 3ʹ,4ʹ-dihydroxyflavonol, an antioxidant and antihypertensive flavonoid, to other known antihypertensives, to provide dual action compounds for the treatment of hypertension.
Language eng
Field of Research 030499 Medicinal and Biomolecular Chemistry not elsewhere classified
030503 Organic Chemical Synthesis
Socio Economic Objective 860803 Human Pharmaceutical Treatments (e.g. Antibiotics)
Description of original xxvi, 274 pages : diagrams, tables, graphs, some coloured
Copyright notice ©The Author. All Rights Reserved
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30061908

Document type: Thesis
Collections: Higher degree theses (full text)
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Created: Tue, 25 Mar 2014, 11:16:32 EST by Belinda Lee

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.