Isolation and characterisation of the ylmE homologue of Thermus thermophilus

Spada, Stefania, Gibert, Yann, Pembroke, J.Tony and Wall, J. Gerard 2001, Isolation and characterisation of the ylmE homologue of Thermus thermophilus, Mitochondrial DNA, vol. 11, no. 6, pp. 507-514, doi: 10.3109/10425170109041334.

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Title Isolation and characterisation of the ylmE homologue of Thermus thermophilus
Author(s) Spada, Stefania
Gibert, Yann
Pembroke, J.Tony
Wall, J. Gerard
Journal name Mitochondrial DNA
Volume number 11
Issue number 6
Start page 507
End page 514
Total pages 8
Publisher Informa Healthcare
Place of publication London, Eng.
Publication date 2001
ISSN 1940-1736
Keyword(s) Thermus thermophilus
proline synthetase cotranscribed (PROSC)
Summary Screening of a Thermus thermophilus genomic library led to the identification of a homologue of the ylmE gene. ylmE is highly conserved in widely divergent organisms from prokaryotes to mammals, suggesting an important, albeit currently unknown, cellular function. The 633 bp gene has a GC content of 69.2% overall and 90% in the third nucleotide position, while the gene product is predicted to be a soluble cytoplasmic protein of 23441 Da. It belongs to a family of conserved proteins of unknown function and exhibits amino acid identities ranging from 45% to 28% to the Aquifex aeolicus and Saccharomyces cerevisiae family members, respectively. We speculate that the gene product may be involved in a cellular stress response in T. thermophilus.
Language eng
DOI 10.3109/10425170109041334
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2001, Informa Healthcare
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Document type: Journal Article
Collection: School of Medicine
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