Investigating retention characteristics of a mixed-mode stationary phase and the enhancement of monolith selectivity for high-performance liquid chromatography

Bassanese, Danielle N., Soliven, Arianne, Stevenson, Paul G., Dennis, Gary R., Barnett, Neil W., Shalliker, R. Andrew and Conlan, Xavier A. 2014, Investigating retention characteristics of a mixed-mode stationary phase and the enhancement of monolith selectivity for high-performance liquid chromatography, Journal of separation science, vol. 37, no. 15, pp. 1937-1943, doi: 10.1002/jssc.201400201.

Attached Files
Name Description MIMEType Size Downloads

Title Investigating retention characteristics of a mixed-mode stationary phase and the enhancement of monolith selectivity for high-performance liquid chromatography
Author(s) Bassanese, Danielle N.ORCID iD for Bassanese, Danielle N. orcid.org/0000-0001-6822-7963
Soliven, Arianne
Stevenson, Paul G.ORCID iD for Stevenson, Paul G. orcid.org/0000-0001-6780-6859
Dennis, Gary R.
Barnett, Neil W.
Shalliker, R. Andrew
Conlan, Xavier A.ORCID iD for Conlan, Xavier A. orcid.org/0000-0003-0829-0551
Journal name Journal of separation science
Volume number 37
Issue number 15
Start page 1937
End page 1943
Total pages 7
Publisher Wiley
Place of publication Weinheim, Germany
Publication date 2014-08
ISSN 1615-9306
1615-9314
Keyword(s) aromatic selectivity
cyano columns
methylene selectivity
mixed-mode columns
phenyl columns
Summary The synthesis and chromatographic behavior of an analytical size mixed-mode bonded silica monolith was investigated. The monolith was functionalized by an in situ modification process of a bare silica rod with chloro(3-cyanopropyl)dimethyl silane and chlorodimethyl propyl phenyl silane solutions. These ligands were selected in order to combine both resonance and nonresonance π-type bonding within a single separation environment. Selectivity studies were undertaken using n-alkyl benzenes and polycyclic aromatic hydrocarbons in aqueous methanol and acetonitrile mobile phases to assess the methylene and aromatic selectivities of the column. The results fit with the linear solvent strength theory suggesting excellent selectivity of the column was achieved. Comparison studies were performed on monolithic columns that were functionalized separately with cyano and phenyl ligands, suggesting highly conjugated molecules were able to successfully exploit both of the π-type selectivities afforded by the two different ligands on the mixed-mode column.
Language eng
DOI 10.1002/jssc.201400201
Field of Research 030108 Separation Science
Socio Economic Objective 970103 Expanding Knowledge in the Chemical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2014, Wiley
Persistent URL http://hdl.handle.net/10536/DRO/DU:30063653

Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 8 times in TR Web of Science
Scopus Citation Count Cited 8 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 584 Abstract Views, 2 File Downloads  -  Detailed Statistics
Created: Wed, 28 May 2014, 09:09:17 EST by Paul Stevenson

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.