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Mortality and use of the auxiliary score in extensive toxic epidermal necrolysis patients admitted to an adult burns referral centre

Mahar, Patrick D., Wasiak, Jason, Cleland, Heather, Watters, David, Eldho, Paul, Marsh, Philip and Gin, Douglas 2013, Mortality and use of the auxiliary score in extensive toxic epidermal necrolysis patients admitted to an adult burns referral centre, Dermatology, vol. 227, no. 2, pp. 180-185, doi: 10.1159/000354264.

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Title Mortality and use of the auxiliary score in extensive toxic epidermal necrolysis patients admitted to an adult burns referral centre
Author(s) Mahar, Patrick D.
Wasiak, Jason
Cleland, Heather
Watters, David
Eldho, Paul
Marsh, Philip
Gin, Douglas
Journal name Dermatology
Volume number 227
Issue number 2
Start page 180
End page 185
Publisher S Karger AG
Place of publication Basel, Switzerland
Publication date 2013-11
ISSN 1018-8665
Keyword(s) Auxiliary score
Necrolysis
SCORTEN
Toxic epidermal necrolysis
Summary  Background: Toxic epidermal necrolysis (TEN) is a rare but fatal condition characterised by cutaneous exfoliation of the dermoepidermal layer and mucosal surfaces. Extensive TEN with epidermal detachment >30% of the total body surface area has been associated with a high mortality. Objective: This study aims to evaluate factors associated with mortality in extensive TEN. In the absence of data to qualify scoring systems such as SCORTEN, this study also aims to evaluate the use of the auxiliary score as a tool for calculating expected mortality. Methods: A retrospective chart review of all patients presenting to our burns service with extensive TEN was undertaken. Application and evaluation of the auxiliary score was also undertaken for this patient population. Results: In extensive TEN, age and delay in admission to a burns centre were factors associated with mortality. Applying the auxiliary score to our patient population, there were no significant differences between expected mortality and observed mortality. Conclusion: Mortality was associated with age and delay in definitive treatment in extensive TEN. Whilst SCORTEN is the gold standard prognostic tool for patients with TEN, in the absence of SCORTEN values, the auxiliary score provides an alternative scoring system to evaluate expected mortality.
Language eng
DOI 10.1159/000354264
Field of Research 110323 Surgery
110304 Dermatology
Socio Economic Objective 920117 Skin and Related Disorders
HERDC Research category C1.1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30066159

Document type: Journal Article
Collection: School of Medicine
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Created: Mon, 22 Sep 2014, 16:11:02 EST by Penny Andrews

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