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Youth depression alleviation: the Fish Oil Youth Depression Study (YoDA-F): A randomized, double-blind, placebo-controlled treatment trial.

Rice, Simon M., Hickie, Ian B., Yung, Alison R., Mackinnon, Andrew, Berk, Michael, Davey, Christopher, Hermens, Daniel F., Hetrick, Sarah E., Parker, Alexandra G., Schäfer, Miriam R., McGorry, Patrick D. and Amminger, G. Paul 2016, Youth depression alleviation: the Fish Oil Youth Depression Study (YoDA-F): A randomized, double-blind, placebo-controlled treatment trial., Early intervention in psychiatry, vol. 10, no. 4, pp. 290-299, doi: 10.1111/eip.12166.

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Title Youth depression alleviation: the Fish Oil Youth Depression Study (YoDA-F): A randomized, double-blind, placebo-controlled treatment trial.
Author(s) Rice, Simon M.
Hickie, Ian B.
Yung, Alison R.
Mackinnon, Andrew
Berk, MichaelORCID iD for Berk, Michael orcid.org/0000-0002-5554-6946
Davey, Christopher
Hermens, Daniel F.
Hetrick, Sarah E.
Parker, Alexandra G.
Schäfer, Miriam R.
McGorry, Patrick D.
Amminger, G. Paul
Journal name Early intervention in psychiatry
Volume number 10
Issue number 4
Start page 290
End page 299
Total pages 10
Publisher Wiley
Place of publication London, Eng.
Publication date 2016-08
ISSN 1751-7893
Keyword(s) adolescent
major depressive disorder
omega-3 fatty acid
randomized control trial
young adult
Summary US authorities have recommended 'black-box' warnings for antidepressants because of the increased risk of suicidality for individuals up to age 25. There is thus a clinical and ethical imperative to provide effective treatment for youth depression with an acceptable risk-benefit balance. Long-chain omega-3 polyunsaturated fatty acids (PUFAs) play an important role in a range of physiological processes in living organisms. Supplementation with omega-3 PUFAs has been shown to have a range of beneficial effects on both physical and mental health, and results of previous trials suggest that omega-3 PUFAs may be a safe and effective treatment for depression. However, conclusions from these trials have been limited by their relatively small sample sizes.
Language eng
DOI 10.1111/eip.12166
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 920410 Mental Health
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2016, Wiley
Persistent URL http://hdl.handle.net/10536/DRO/DU:30067213

Document type: Journal Article
Collection: School of Medicine
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