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Prediction of the likelihood of drug interactions with kinase inhibitors based on in vitro and computational studies

Wang, Zhi-Xin, Sun, Jiazhi, Howell, Caitlin E., Zhou, Qing-Yu, He, Zhi-Xu, Yang, Tianxin, Chew, Helen, Duan, Wei, Zhou, Zhi -Wei, Kanwar, Jagat R. and Zhou, Shu-Feng 2014, Prediction of the likelihood of drug interactions with kinase inhibitors based on in vitro and computational studies, Fundamental & clinical pharmacology, vol. 28, no. 5, pp. 551-582, doi: 10.1111/fcp.12069.

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Title Prediction of the likelihood of drug interactions with kinase inhibitors based on in vitro and computational studies
Author(s) Wang, Zhi-Xin
Sun, Jiazhi
Howell, Caitlin E.
Zhou, Qing-Yu
He, Zhi-Xu
Yang, Tianxin
Chew, Helen
Duan, WeiORCID iD for Duan, Wei orcid.org/0000-0001-5782-9184
Zhou, Zhi -Wei
Kanwar, Jagat R.
Zhou, Shu-Feng
Journal name Fundamental & clinical pharmacology
Volume number 28
Issue number 5
Start page 551
End page 582
Total pages 32
Publisher Wiley-Blackwell
Place of publication Abingdon, England
Publication date 2014-10
ISSN 1472-8206
Keyword(s) CYP3A4
drug interaction
high-throughput
kinase inhibitor
molecular docking
toxicity
Science & Technology
Life Sciences & Biomedicine
Pharmacology & Pharmacy
CELL LUNG-CANCER
CHRONIC MYELOGENOUS LEUKEMIA
HUMAN CYTOCHROME-P450 1A2
CHRONIC MYELOID-LEUKEMIA
PHASE-I
TYROSINE KINASE
BREAST-CANCER
1ST-LINE TREATMENT
PANCREATIC-CANCER
Language eng
DOI 10.1111/fcp.12069
Field of Research 111299 Oncology and Carcinogenesis not elsewhere classified
Socio Economic Objective 920102 Cancer and Related Disorders
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2014, Wiley-Blackwell
Persistent URL http://hdl.handle.net/10536/DRO/DU:30067331

Document type: Journal Article
Collection: School of Medicine
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Created: Mon, 08 Dec 2014, 12:35:29 EST

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