Natural antioxidant biomolecules promises future nanomedicine based therapy for cataract

Sunkireddy, Pavan, Jha, Shashi Nath, Kanwar, Jagat R. and Yadav, Subhash C. 2013, Natural antioxidant biomolecules promises future nanomedicine based therapy for cataract, Colloids and surfaces b: biointerfaces, vol. 112, pp. 554-562, doi: 10.1016/j.colsurfb.2013.07.068.

Attached Files
Name Description MIMEType Size Downloads

Title Natural antioxidant biomolecules promises future nanomedicine based therapy for cataract
Author(s) Sunkireddy, Pavan
Jha, Shashi Nath
Kanwar, Jagat R.ORCID iD for Kanwar, Jagat R.
Yadav, Subhash C.
Journal name Colloids and surfaces b: biointerfaces
Volume number 112
Start page 554
End page 562
Total pages 9
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2013-12
ISSN 1873-4367
Keyword(s) Ayurvedic treatment
Oxidative modification
Phase separation
Medicine, Ayurvedic
Osmotic Pressure
Phase Transition
Protein Conformation
Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Chemistry, Physical
Materials Science, Biomaterials
Materials Science
Summary Cataract is an eye disease of major human concern and its prevention is important to control the global incidences of blindness. The emergence of cataract in the eye lens by strong UV radiation and growing pollution could be effectively reduced by natural antioxidant biomolecules such as flavonoids, phenolic acids, carotenoids and vitamins. This goal can be achieved either by direct external use of antioxidant biomolecules in the form of topical application as an eye drops, food supplements or through nanobiotechnology based formulation without any side effects. In this manuscript, we have discussed the mechanisms of cataract formation and the preventive role of different classes of natural antioxidant biomolecules. Further, role of nanobiotechnology to enhance therapeutic potential of these natural antioxidant molecules by enhancing solubility, stability, bioavailability and sustained release has been briefly discussed.
Language eng
DOI 10.1016/j.colsurfb.2013.07.068
Field of Research 119999 Medical and Health Sciences not elsewhere classified
0306 Physical Chemistry (Incl. Structural)
0903 Biomedical Engineering
0904 Chemical Engineering
Socio Economic Objective 929999 Health not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2013, Elsevier B.V.
Persistent URL

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Connect to link resolver
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 21 times in TR Web of Science
Scopus Citation Count Cited 24 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 208 Abstract Views, 3 File Downloads  -  Detailed Statistics
Created: Mon, 02 Feb 2015, 10:43:53 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact