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STin2 VNTR polymorphism is associated with comorbid tobacco use and mood disorders.

Pizzo de Castro,MR, Vargas Nunes,SO, Guembarovski,RL, Ariza,CB, Oda,JM, Vargas,HO, Piccoli de Melo,LG, Watanabe,MA, Berk,M and Maes,M 2015, STin2 VNTR polymorphism is associated with comorbid tobacco use and mood disorders., Journal of Affective Disorders, vol. 172, pp. 347-354, doi: 10.1016/j.jad.2014.10.023.

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Title STin2 VNTR polymorphism is associated with comorbid tobacco use and mood disorders.
Author(s) Pizzo de Castro,MR
Vargas Nunes,SO
Guembarovski,RL
Ariza,CB
Oda,JM
Vargas,HO
Piccoli de Melo,LG
Watanabe,MA
Berk,MORCID iD for Berk,M orcid.org/0000-0002-5554-6946
Maes,M
Journal name Journal of Affective Disorders
Volume number 172
Start page 347
End page 354
Total pages 8
Publisher Elsevier
Place of publication Amsterdam , Netherlands
Publication date 2015-02-01
ISSN 1573-2517
Keyword(s) Genetic polymorphism
Inflammation
Mood disorders
Oxidative stress
Serotonin transporter
Tobacco use disorder
Science & Technology
Life Sciences & Biomedicine
Clinical Neurology
Psychiatry
Neurosciences & Neurology
SEROTONIN TRANSPORTER GENE
MAJOR DEPRESSIVE DISORDER
OBSTRUCTIVE PULMONARY-DISEASE
CIGARETTE-SMOKING
NICOTINE-DEPENDENCE
BIPOLAR DISORDER
FOLLOW-UP
PSYCHIATRIC-DISORDERS
SUICIDAL-BEHAVIOR
MENTAL-HEALTH
Summary There is a significant comorbidity between mood disorders and tobacco use disorder (TUD), which may be related to both genetic and environmental factors. Gene variants of the 5-HT transporter, such as STin2 VNTR (a variable number of tandem repeats in the functional serotonin transporter intron 2) may be associated with mood disorders and TUD.
Language eng
DOI 10.1016/j.jad.2014.10.023
Field of Research 110999 Neurosciences not elsewhere classified
Socio Economic Objective 920209 Mental Health Services
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2015, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30069442

Document type: Journal Article
Collection: School of Medicine
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