Ti-SrO metal matrix composites for bone implant materials

Wang,Y, Wong,C, Wen,C, Hodgson,P and Li,Y 2014, Ti-SrO metal matrix composites for bone implant materials, Journal of Materials Chemistry B, vol. 2, no. 35, pp. 5854-5861, doi: 10.1039/c4tb00372a.

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Title Ti-SrO metal matrix composites for bone implant materials
Author(s) Wang,YORCID iD for Wang,Y orcid.org/0000-0002-9807-2293
Wong,C
Wen,C
Hodgson,P
Li,Y
Journal name Journal of Materials Chemistry B
Volume number 2
Issue number 35
Start page 5854
End page 5861
Publisher Royal Society of Chemistry
Place of publication London, Eng.
Publication date 2014-09
ISSN 2050-7518
2050-750X
Keyword(s) Science & Technology
Technology
Materials Science, Biomaterials
Materials Science
HYDROXYAPATITE COATINGS
POWDER-METALLURGY
SURFACE-ENERGY
CELL RESPONSE
PARTICLE-SIZE
TITANIUM
STRONTIUM
SCAFFOLDS
ALLOYS
Summary Titanium-strontia (Ti-SrO) metal matrix composites (MMCs) with 0, 1, 3 and 5% (weight ratio) of SrO have been fabricated through the powder metallurgy method. Increasing the weight ratio of SrO from 0 to 5%, the compressive strength of Ti-SrO MMCs increased from 982 MPa to 1753 MPa, while the ultimate strain decreased from 0.28 to 0.05. The elastic moduli of Ti-3SrO and Ti-5SrO MMCs were higher than those of Ti and Ti-1SrO MMC samples. Additionally, the micro hardness of Ti-SrO MMCs was enhanced from 59% to 190% with the addition of SrO. The enhanced compression strength and micro hardness of Ti-SrO MMCs were attributed to the Hall-Petch effect and the SrO dispersion strengthening in the Ti matrix. MTS assay results demonstrated that Ti-SrO MMCs with 3% SrO exhibited enhanced proliferation of osteoblast-like cells. Alkaline phosphatase activity of cells was not influenced significantly on the surface of Ti-SrO MMCs compared with pure Ti in a term longer than 10 days. The cell morphology on the Ti-SrO MMCs was observed using confocal microscopy and scanning electron microscopy, which confirmed that the Ti-3%SrO MMCs showed optimal in vitro biocompatibility. This journal is © the Partner Organisations 2014.
Language eng
DOI 10.1039/c4tb00372a
Field of Research 030306 Synthesis of Materials
030301 Chemical Characterisation of Materials
060106 Cellular Interactions (incl Adhesion, Matrix, Cell Wall)
Socio Economic Objective 970103 Expanding Knowledge in the Chemical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2014, Royal Society of Chemistry
Persistent URL http://hdl.handle.net/10536/DRO/DU:30069821

Document type: Journal Article
Collection: Institute for Frontier Materials
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