The role of obesity duration on the association between obesity and risk of physical disability

Wong, Evelyn, Tanamas, Stephanie K., Wolfe, Rory, Backholer, Kathryn, Stevenson, Christopher, Abdullah, Asnawi and Peeters, Anna 2015, The role of obesity duration on the association between obesity and risk of physical disability, Obesity, vol. 23, no. 2, pp. 443-447, doi: 10.1002/oby.20936.

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Title The role of obesity duration on the association between obesity and risk of physical disability
Author(s) Wong, Evelyn
Tanamas, Stephanie K.
Wolfe, Rory
Backholer, KathrynORCID iD for Backholer, Kathryn orcid.org/0000-0002-3323-575X
Stevenson, ChristopherORCID iD for Stevenson, Christopher orcid.org/0000-0003-4026-5719
Abdullah, Asnawi
Peeters, AnnaORCID iD for Peeters, Anna orcid.org/0000-0003-4340-9132
Journal name Obesity
Volume number 23
Issue number 2
Start page 443
End page 447
Total pages 5
Publisher Wiley
Place of publication London, Eng.
Publication date 2015-02
ISSN 1930-7381
1930-739X
Summary Objective To relate measured obesity duration in mid-life with subsequent incidence of physical disability over and above body mass index (BMI) attained. Methods Framingham Offspring Study is a longitudinal study that began in 1971. Examination 5 (1991-1995; "baseline") and disability onset ascertained from examinations 6-8 (2008) were used. About 2,095 disability-free participants aged 45-65 years at baseline were included. Obesity (BMI- ≥- 30 kg/m2) duration was calculated between examination 1 and examination 5. Cox regression was used to analyze time to disability. Results 204 participants developed disability (incidence rate = 7.9 per 1,000 person-years). Obesity duration ranged from 0 to 22 years (mean of 2.0 years overall, 8.3 years for those with baseline obesity). Obesity duration increased risk of new disability (hazard ratio [HR] 1.07 per year of obesity; 95% confidence interval [CI] 1.05-1.09). This association was attenuated on further adjustment for baseline BMI (HR 1.03; 95% CI 1.00-1.06). Conclusions Being obese for longer during mid-life increases the risk of later-life disability over and above attained BMI. These results support the need for prevention of weight gain in young adults to avoid an increasing burden of physical disability in later life.
Language eng
DOI 10.1002/oby.20936
Field of Research 111706 Epidemiology
Socio Economic Objective 920499 Public Health (excl. Specific Population Health) not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Grant ID DP120103277
Copyright notice ©2015, Wiley
Persistent URL http://hdl.handle.net/10536/DRO/DU:30070056

Document type: Journal Article
Collections: Faculty of Health
School of Health and Social Development
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