Silk films as a repair material for perforations of the tympanic membrane
Allardyce,BJ, Rajkhowa,, Atlas,MD, Dilley,RJ and Wang,X 2014, Silk films as a repair material for perforations of the tympanic membrane, in Proceedings of the 89th Textile Institute World Conference, Fiber Society, [Wuhan, China], pp. 6-10.
Proceedings of the 89th Textile Institute World Conference
Textile Institute World Conference
Place of publication
Large, chronic perforations of the tympanic membrane or eardrum can cause hearing loss as well as a range of secondary health problems. Current methods of repair usually involve grafting a material such as cartilage from another site on the body across the perforation. However, given problems such as possible infections at the graft donor site and the inability to see through the graft to assess infection within the middle ear, there is a need to develop an alternative material that is strong, readily available and transparent. Such a material would allow for less invasive surgery and potentially result in a superior hearing outcome for the patient. Our recent work has identified silk fibroin films as a promising material for this application. This paper reviews the repair of large perforations and compares the mechanical properties of silk with some existing graft materials. It also briefly discusses the difficulties in defining and comparing these properties with such different materials.
Field of Research
090399 Biomedical Engineering not elsewhere classified
Socio Economic Objective
970111 Expanding Knowledge in the Medical and Health Sciences
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